| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20017201 | HPV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS20017202 | HPV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS20039910 | HPV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS20036459 | HPV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS44012280 | HTLV-1 | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS44027485 | HTLV-1 | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS44014592 | HTLV-1 | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS44006953 | HTLV-1 | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS44032797 | HTLV-1 | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS44027486 | HTLV-1 | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PRKCA |
|---|---|
| DrugBank ID | DB00144 |
| Drug Name | Phosphatidyl serine |
| Target ID | BE0001132 |
| UniProt ID | P17252 |
| Regulation Type | |
| PubMed IDs | 12269833; 14698304; 16114872; 17367165 |
| Citations | Yu D, Kazanietz MG, Harvey RG, Penning TM: Polycyclic aromatic hydrocarbon o-quinones inhibit the activity of the catalytic fragment of protein kinase C. Biochemistry. 2002 Oct 1;41(39):11888-94.@@Rodriguez-Alfaro JA, Gomez-Fernandez JC, Corbalan-Garcia S: Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha. J Mol Biol. 2004 Jan 23;335(4):1117-29.@@Lopez-Andreo MJ, Torrecillas A, Conesa-Zamora P, Corbalan-Garcia S, Gomez-Fernandez JC: Retinoic acid as a modulator of the activity of protein kinase Calpha. Biochemistry. 2005 Aug 30;44(34):11353-60.@@Corbin JA, Evans JH, Landgraf KE, Falke JJ: Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity. Biochemistry. 2007 Apr 10;46(14):4322-36. Epub 2007 Mar 17. |
| Groups | Investigational; Nutraceutical |
| Direct Classification | |
| SMILES | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC |
| Pathways | Phosphatidylcholine Biosynthesis PC(14:0/20:0); Phosphatidylcholine Biosynthesis PC(14:0/20:4(5Z,8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/20:3(8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/16:0); Phosphatidylcholine Biosynthesis PC(14:0/20:5(5Z,8Z,11Z,14Z,17Z)); Phosphatidylcholine Biosynthesis PC(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/16:0); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(14:0/20:2(11Z,14Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/22:2(13Z,16Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/24:0); Phosphatidylcholine Biosynthesis PC(14:0/15:0); Phosphatidylcholine Biosynthesis PC(15:0/14:0); Phosphatidylcholine Biosynthesis PC(15:0/20:4(5Z,8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); Phosphatidylcholine Biosynthesis PC(14:0/20:1(11Z)); Phosphatidylcholine Biosynthesis PC(16:0/16:0); Phosphatidylcholine Biosynthesis PC(16:0/14:0); Phosphatidylcholine Biosynthesis PC(15:0/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(14:0/22:5(4Z,7Z,10Z,13Z,16Z)); Phosphatidylcholine Biosynthesis PC(15:0/22:0); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/14:0); Phosphatidylcholine Biosynthesis PC(15:0/20:1(11Z)); Phosphatidylcholine Biosynthesis PC(14:0/18:2(9Z,12Z)); Phosphatidylcholine Biosynthesis PC(14:0/14:0); Phosphatidylcholine Biosynthesis PC(14:0/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(16:0/18:1(9Z)); Phosphatidylcholine Biosynthesis PC(15:0/18:0); Phosphatidylcholine Biosynthesis PC(16:0/14:1(9Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/18:3(9Z,12Z,15Z)) |
| PharmGKB | PA164768860 |
| ChEMBL | CHEMBL4297669 |
