Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44045810HTLV-1ENSG00000253729.9protein_codingPRKDCYesYes5591P78527
TVIS44045908HTLV-1ENSG00000253729.9protein_codingPRKDCYesYes5591P78527
TCGA Plot Options
Drug Information
GenePRKDC
DrugBank IDDB00201
Drug NameCaffeine
Target IDBE0002385
UniProt IDP78527
Regulation Typeinhibitor
PubMed IDs12145276
CitationsFoukas LC, Daniele N, Ktori C, Anderson KE, Jensen J, Shepherd PR: Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities. J Biol Chem. 2002 Oct 4;277(40):37124-30. Epub 2002 Jul 26.
GroupsApproved
Direct ClassificationXanthines
SMILESCN1C=NC2=C1C(=O)N(C)C(=O)N2C
PathwaysCaffeine Metabolism
PharmGKBPA448710
ChEMBLCHEMBL113