| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30046305 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS30046306 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS30046307 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS30046308 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS30046309 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS30046310 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS30046311 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS30046312 | HIV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS20020416 | HPV | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
| TVIS44009311 | HTLV-1 | ENSG00000067900.9 | protein_coding | ROCK1 | No | No | 6093 | Q13464 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ROCK1 |
|---|---|
| DrugBank ID | DB04707 |
| Drug Name | Hydroxyfasudil |
| Target ID | BE0001016 |
| UniProt ID | Q13464 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 10592235 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Isoquinolones and derivatives |
| SMILES | O=C1NC=CC2=C(C=CC=C12)S(=O)(=O)N1CCCNCC1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1233300 |
