| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30072851 | HIV | ENSG00000177189.14 | protein_coding | RPS6KA3 | No | No | 6197 | B4DG22 B7ZB17 P51812 |
| TVIS20064639 | HPV | ENSG00000177189.14 | protein_coding | RPS6KA3 | No | No | 6197 | B4DG22 B7ZB17 P51812 |
| TVIS20064265 | HPV | ENSG00000177189.14 | protein_coding | RPS6KA3 | No | No | 6197 | B4DG22 B7ZB17 P51812 |
| TVIS20032301 | HPV | ENSG00000177189.14 | protein_coding | RPS6KA3 | No | No | 6197 | B4DG22 B7ZB17 P51812 |
| TVIS44051781 | HTLV-1 | ENSG00000177189.14 | protein_coding | RPS6KA3 | No | No | 6197 | B4DG22 B7ZB17 P51812 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RPS6KA3 |
|---|---|
| DrugBank ID | DB00945 |
| Drug Name | Acetylsalicylic acid |
| Target ID | BE0004876 |
| UniProt ID | P51812 |
| Regulation Type | inhibitor |
| PubMed IDs | 10553090; 21142801; 9817196 |
| Citations | Stevenson MA, Zhao MJ, Asea A, Coleman CN, Calderwood SK: Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes. J Immunol. 1999 Nov 15;163(10):5608-16.@@Stratford AL, Dunn SE: The promise and challenges of targeting RSK for the treatment of cancer. Expert Opin Ther Targets. 2011 Jan;15(1):1-4. doi: 10.1517/14728222.2011.537656.@@O'Neill EA: A new target for aspirin. Nature. 1998 Nov 5;396(6706):15, 17. doi: 10.1038/23810. |
| Groups | Approved; Vet_approved |
| Direct Classification | Acylsalicylic acids |
| SMILES | CC(=O)OC1=CC=CC=C1C(O)=O |
| Pathways | Acetylsalicylic Acid Action Pathway |
| PharmGKB | PA448497 |
| ChEMBL | CHEMBL25 |
