| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017865 | HBV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS10050166 | HBV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30000162 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30005619 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30005620 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30027790 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30027791 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30027792 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30027793 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
| TVIS30027794 | HIV | ENSG00000166224.19 | protein_coding | SGPL1 | No | No | 8879 | O95470 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SGPL1 |
|---|---|
| DrugBank ID | DB00114 |
| Drug Name | Pyridoxal phosphate |
| Target ID | BE0000778 |
| UniProt ID | O95470 |
| Regulation Type | cofactor |
| PubMed IDs | 15522238; 11377878 |
| Citations | Ikeda M, Kihara A, Igarashi Y: Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol. Biochem Biophys Res Commun. 2004 Dec 3;325(1):338-43.@@Bobbin RP: PPADS, an ATP antagonist, attenuates the effects of a moderately intense sound on cochlear mechanics. Hear Res. 2001 Jun;156(1-2):10-6. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Pyridoxals and derivatives |
| SMILES | CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O |
| Pathways | Histidinemia; 3-Methylglutaconic Aciduria Type I; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); beta-Ketothiolase Deficiency; Tyrosine Metabolism; Disulfiram Action Pathway; Hyperprolinemia Type II; Glutamate Metabolism; Argininosuccinic Aciduria; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; Porphyrin Metabolism; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Taurine and Hypotaurine Metabolism; Catecholamine Biosynthesis; Glycine and Serine Metabolism; Carnitine Synthesis; Tyrosinemia Type 3 (TYRO3); Selenoamino Acid Metabolism; Carbamoyl Phosphate Synthetase Deficiency; Hyperprolinemia Type I; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Cystathionine beta-Synthase Deficiency; Arginine and Proline Metabolism; Starch and Sucrose Metabolism; Globoid Cell Leukodystrophy; Ammonia Recycling |
| PharmGKB | PA164749650 |
| ChEMBL | CHEMBL82202 |
