| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20062238 | HPV | ENSG00000059377.19 | protein_coding | TBXAS1 | No | No | 6916 | P24557 |
| TVIS44022677 | HTLV-1 | ENSG00000059377.19 | protein_coding | TBXAS1 | No | No | 6916 | P24557 |
| TVIS44045702 | HTLV-1 | ENSG00000059377.19 | protein_coding | TBXAS1 | No | No | 6916 | P24557 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | TBXAS1 |
|---|---|
| DrugBank ID | DB01207 |
| Drug Name | Ridogrel |
| Target ID | BE0001893 |
| UniProt ID | P24557 |
| Regulation Type | inhibitor |
| PubMed IDs | 11270983; 11856082; 8313547; 8376914; 10848666; 10592235 |
| Citations | Park SJ, Lee JJ, Vanhoutte PM: Endothelin-1 releases endothelium-derived endoperoxides and thromboxane A2 in porcine coronary arteries with regenerated endothelium. Zhongguo Yao Li Xue Bao. 1999 Oct;20(10):872-8.@@Tytgat GN, Van Nueten L, Van De Velde I, Joslyn A, Hanauer SB: Efficacy and safety of oral ridogrel in the treatment of ulcerative colitis: two multicentre, randomized, double-blind studies. Aliment Pharmacol Ther. 2002 Jan;16(1):87-99.@@Authors unspecified: Randomized trial of ridogrel, a combined thromboxane A2 synthase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor antagonist, versus aspirin as adjunct to thrombolysis in patients with acute myocardial infarction. The Ridogrel Versus Aspirin Patency Trial (RAPT). Circulation. 1994 Feb;89(2):588-95.@@De Cree J, Geukens H, Gutwirth P, De Clerck F, Vercammen E, Verhaegen H: The effect of a combined administration of ridogrel and ketanserin in patients with intermittent claudication. Int Angiol. 1993 Mar;12(1):59-68.@@Carty E, Macey M, McCartney SA, Rampton DS: Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. Aliment Pharmacol Ther. 2000 Jun;14(6):807-17.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Trifluoromethylbenzenes |
| SMILES | OC(=O)CCCCON=C(C1=CN=CC=C1)C1=CC(=CC=C1)C(F)(F)F |
| Pathways | |
| PharmGKB | PA164746413 |
| ChEMBL | CHEMBL280728 |
