GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process |
1847 |
61.737 |
2.1381 |
0 |
0 |
GO:0051276 |
chromosome organization |
1143 |
38.205 |
2.8268 |
0 |
0 |
GO:0016569 |
covalent chromatin modification |
468 |
15.643 |
3.7716 |
0 |
0 |
GO:0016570 |
histone modification |
455 |
15.209 |
3.8794 |
0 |
0 |
GO:0043401 |
steroid hormone mediated signaling pathway |
189 |
6.3174 |
3.4825 |
3.71E-7 |
0 |
GO:0010638 |
positive regulation of organelle organization |
600 |
20.055 |
2.2438 |
3.65E-7 |
0 |
GO:0000226 |
microtubule cytoskeleton organization |
540 |
18.05 |
2.3269 |
3.46E-7 |
0 |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
676 |
22.596 |
2.1686 |
3.01E-7 |
0 |
GO:0006281 |
DNA repair |
511 |
17.08 |
2.4004 |
2.11E-7 |
0 |
GO:0045652 |
regulation of megakaryocyte differentiation |
53 |
1.7715 |
6.7738 |
1.32E-7 |
0 |
GO:0006325 |
chromatin organization |
741 |
24.768 |
3.2703 |
0 |
0 |
GO:0051254 |
positive regulation of RNA metabolic process |
1668 |
55.754 |
2.1344 |
4.44E-16 |
6.73E-13 |
GO:1902680 |
positive regulation of RNA biosynthetic process |
1584 |
52.946 |
2.0965 |
2.2E-14 |
2.5E-11 |
GO:1903508 |
positive regulation of nucleic acid-templated transcription |
1583 |
52.912 |
2.0978 |
2.11E-14 |
2.5E-11 |
GO:0010557 |
positive regulation of macromolecule biosynthetic process |
1826 |
61.035 |
1.9989 |
2.64E-14 |
2.67E-11 |
GO:0010628 |
positive regulation of gene expression |
1911 |
63.876 |
1.9569 |
5.51E-14 |
5.01E-11 |
GO:0007049 |
cell cycle |
1739 |
58.127 |
2.0128 |
6.45E-14 |
5.33E-11 |
GO:0002429 |
immune response-activating cell surface receptor signaling pathway |
300 |
10.028 |
3.989 |
7.16E-14 |
5.43E-11 |
GO:0002768 |
immune response-regulating cell surface receptor signaling pathway |
330 |
11.03 |
3.8077 |
8.42E-14 |
5.89E-11 |
GO:0002682 |
regulation of immune system process |
1400 |
46.795 |
2.137 |
1.79E-13 |
9.56E-11 |
GO:0018193 |
peptidyl-amino acid modification |
1212 |
40.511 |
2.2463 |
1.58E-13 |
9.56E-11 |
GO:0022402 |
cell cycle process |
1274 |
42.584 |
2.2074 |
1.65E-13 |
9.56E-11 |
GO:0031328 |
positive regulation of cellular biosynthetic process |
1919 |
64.143 |
1.9332 |
1.74E-13 |
9.56E-11 |
GO:0009891 |
positive regulation of biosynthetic process |
1949 |
65.146 |
1.9188 |
2.3E-13 |
1.16E-10 |
GO:0006468 |
protein phosphorylation |
1860 |
62.171 |
1.9302 |
5.38E-13 |
2.57E-10 |
GO:0045893 |
positive regulation of transcription, DNA-templated |
1499 |
50.105 |
2.0557 |
8.16E-13 |
3.71E-10 |
GO:0000278 |
mitotic cell cycle |
927 |
30.985 |
2.3882 |
2.2E-12 |
9.51E-10 |
GO:0048534 |
hematopoietic or lymphoid organ development |
833 |
27.843 |
2.4782 |
2.44E-12 |
1.01E-9 |
GO:0050851 |
antigen receptor-mediated signaling pathway |
184 |
6.1503 |
4.7152 |
3.21E-12 |
1.27E-9 |
GO:0002520 |
immune system development |
881 |
29.448 |
2.4111 |
4.16E-12 |
1.57E-9 |
GO:0002764 |
immune response-regulating signaling pathway |
485 |
16.211 |
3.0226 |
4.74E-12 |
1.73E-9 |
GO:0030097 |
hemopoiesis |
791 |
26.439 |
2.4963 |
5.58E-12 |
1.89E-9 |
GO:0002757 |
immune response-activating signal transduction |
454 |
15.175 |
3.0972 |
5.61E-12 |
1.89E-9 |
GO:0051726 |
regulation of cell cycle |
1106 |
36.968 |
2.2181 |
5.92E-12 |
1.92E-9 |
GO:0010629 |
negative regulation of gene expression |
1733 |
57.926 |
1.899 |
1.81E-11 |
5.67E-9 |
GO:0006259 |
DNA metabolic process |
970 |
32.423 |
2.2824 |
1.94E-11 |
5.88E-9 |
GO:0018205 |
peptidyl-lysine modification |
360 |
12.033 |
3.3242 |
2.61E-11 |
7.64E-9 |
GO:0002253 |
activation of immune response |
534 |
17.849 |
2.8013 |
4.59E-11 |
1.3E-8 |
GO:0071495 |
cellular response to endogenous stimulus |
1347 |
45.024 |
2.0211 |
5.74E-11 |
1.58E-8 |
GO:0046649 |
lymphocyte activation |
646 |
21.593 |
2.5935 |
6.05E-11 |
1.62E-8 |
GO:0050852 |
T cell receptor signaling pathway |
143 |
4.7798 |
5.0211 |
6.3E-11 |
1.64E-8 |
GO:0033043 |
regulation of organelle organization |
1245 |
41.615 |
2.0666 |
6.9E-11 |
1.74E-8 |
GO:0042110 |
T cell activation |
452 |
15.108 |
2.9123 |
2.06E-10 |
5.05E-8 |
GO:0050778 |
positive regulation of immune response |
706 |
23.598 |
2.4578 |
2.21E-10 |
5.29E-8 |
GO:0007346 |
regulation of mitotic cell cycle |
578 |
19.32 |
2.6398 |
2.46E-10 |
5.74E-8 |
GO:1903706 |
regulation of hemopoiesis |
389 |
13.002 |
3.0763 |
2.79E-10 |
6.28E-8 |
GO:0045637 |
regulation of myeloid cell differentiation |
221 |
7.387 |
3.7904 |
1.41E-9 |
2.52E-7 |
GO:0044403 |
symbiont process |
768 |
25.671 |
2.2983 |
2.01E-9 |
3.45E-7 |
GO:1901990 |
regulation of mitotic cell cycle phase transition |
354 |
11.833 |
3.0424 |
3.01E-9 |
4.41E-7 |
GO:0009719 |
response to endogenous stimulus |
1595 |
53.313 |
1.8194 |
3.58E-9 |
4.97E-7 |
GO:0016571 |
histone methylation |
134 |
4.479 |
4.6886 |
3.61E-9 |
4.97E-7 |
GO:0080134 |
regulation of response to stress |
1361 |
45.492 |
1.8904 |
5.56E-9 |
7.08E-7 |
GO:0018105 |
peptidyl-serine phosphorylation |
282 |
9.4259 |
3.2888 |
6.13E-9 |
7.43E-7 |
GO:0007264 |
small GTPase mediated signal transduction |
552 |
18.451 |
2.4931 |
1.17E-8 |
1.318E-6 |
GO:0045321 |
leukocyte activation |
1184 |
39.576 |
1.9456 |
1.16E-8 |
1.318E-6 |
GO:0032743 |
positive regulation of interleukin-2 production |
30 |
1.0028 |
9.9725 |
2.64E-8 |
2.8238E-6 |
GO:1903507 |
negative regulation of nucleic acid-templated transcription |
1215 |
40.612 |
1.896 |
3.51E-8 |
3.6223E-6 |
GO:0050863 |
regulation of T cell activation |
305 |
10.195 |
3.0408 |
3.88E-8 |
3.8767E-6 |
GO:0009968 |
negative regulation of signal transduction |
1202 |
40.177 |
1.8916 |
4.8E-8 |
4.6903E-6 |
GO:0016055 |
Wnt signaling pathway |
456 |
15.242 |
2.5587 |
8.01E-8 |
7.4313E-6 |
GO:0044265 |
cellular macromolecule catabolic process |
1108 |
37.035 |
1.9171 |
8.35E-8 |
7.6164E-6 |
GO:0006470 |
protein dephosphorylation |
306 |
10.228 |
2.7375 |
1.501E-6 |
0.0001 |
GO:0035723 |
interleukin-15-mediated signaling pathway |
13 |
0.4345 |
13.808 |
1.907E-6 |
0.0001 |
GO:0010452 |
histone H3-K36 methylation |
12 |
0.4011 |
14.959 |
1.0567E-6 |
0.0001 |
GO:0042326 |
negative regulation of phosphorylation |
423 |
14.139 |
2.4047 |
2.2545E-6 |
0.0001 |
GO:0006913 |
nucleocytoplasmic transport |
353 |
11.799 |
2.5426 |
2.9342E-6 |
0.0002 |
GO:0045058 |
T cell selection |
48 |
1.6044 |
6.2328 |
3.3421E-6 |
0.0002 |
GO:0016573 |
histone acetylation |
153 |
5.1141 |
3.5197 |
3.6469E-6 |
0.0002 |
GO:1901699 |
cellular response to nitrogen compound |
614 |
20.523 |
2.0952 |
3.9927E-6 |
0.0002 |
GO:0071363 |
cellular response to growth factor stimulus |
660 |
22.061 |
2.0398 |
4.7777E-6 |
0.0002 |
GO:0050870 |
positive regulation of T cell activation |
197 |
6.5848 |
3.1892 |
2.8746E-6 |
0.0002 |
GO:1905269 |
positive regulation of chromatin organization |
94 |
3.142 |
4.4558 |
2.7506E-6 |
0.0002 |
GO:1902749 |
regulation of cell cycle G2/M phase transition |
167 |
5.582 |
3.4038 |
3.2528E-6 |
0.0002 |
GO:0042325 |
regulation of phosphorylation |
1500 |
50.138 |
1.6355 |
5.4468E-6 |
0.0003 |
GO:0043065 |
positive regulation of apoptotic process |
606 |
20.256 |
2.0735 |
6.7014E-6 |
0.0003 |
GO:0034613 |
cellular protein localization |
1815 |
60.667 |
1.5494 |
9.5999E-6 |
0.0004 |
GO:0051567 |
histone H3-K9 methylation |
32 |
1.0696 |
7.4794 |
7.6671E-6 |
0.0004 |
GO:0000902 |
cell morphogenesis |
982 |
32.824 |
1.7975 |
8.6221E-6 |
0.0004 |
GO:0018107 |
peptidyl-threonine phosphorylation |
106 |
3.5431 |
3.9514 |
0 |
0.0005 |
GO:0050854 |
regulation of antigen receptor-mediated signaling pathway |
57 |
1.9052 |
5.2487 |
0 |
0.0007 |
GO:0000165 |
MAPK cascade |
896 |
29.949 |
1.8031 |
0 |
0.0008 |
GO:0043067 |
regulation of programmed cell death |
1530 |
51.141 |
1.5839 |
0 |
0.0008 |
GO:0070507 |
regulation of microtubule cytoskeleton organization |
175 |
5.8494 |
3.0772 |
0 |
0.0009 |
GO:0032446 |
protein modification by small protein conjugation |
789 |
26.373 |
1.858 |
0 |
0.0009 |
GO:0034067 |
protein localization to Golgi apparatus |
27 |
0.9025 |
7.7564 |
0 |
0.0009 |
GO:0051603 |
proteolysis involved in cellular protein catabolic process |
683 |
22.829 |
1.9273 |
0 |
0.001 |
GO:0001817 |
regulation of cytokine production |
642 |
21.459 |
1.9572 |
0 |
0.001 |
GO:1905244 |
regulation of modification of synaptic structure |
12 |
0.4011 |
12.466 |
0 |
0.001 |
GO:0046785 |
microtubule polymerization |
72 |
2.4066 |
4.5707 |
0 |
0.001 |
GO:0000280 |
nuclear division |
420 |
14.039 |
2.2082 |
0 |
0.0012 |
GO:2001238 |
positive regulation of extrinsic apoptotic signaling pathway |
50 |
1.6713 |
5.3851 |
0 |
0.0013 |
GO:0006303 |
double-strand break repair via nonhomologous end joining |
75 |
2.5069 |
4.3879 |
0 |
0.0013 |
GO:0030010 |
establishment of cell polarity |
132 |
4.4121 |
3.3997 |
0 |
0.0013 |
GO:0045580 |
regulation of T cell differentiation |
133 |
4.4456 |
3.3741 |
0 |
0.0014 |
GO:0046631 |
alpha-beta T cell activation |
133 |
4.4456 |
3.3741 |
0 |
0.0014 |
GO:1903827 |
regulation of cellular protein localization |
504 |
16.846 |
2.0776 |
0 |
0.0014 |
GO:0045086 |
positive regulation of interleukin-2 biosynthetic process |
13 |
0.4345 |
11.507 |
0 |
0.0015 |
GO:0033127 |
regulation of histone phosphorylation |
13 |
0.4345 |
11.507 |
0 |
0.0015 |
GO:0002433 |
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis |
76 |
2.5403 |
4.3302 |
0 |
0.0015 |
GO:0000377 |
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
329 |
10.997 |
2.3643 |
0 |
0.0016 |
GO:0001959 |
regulation of cytokine-mediated signaling pathway |
153 |
5.1141 |
3.1286 |
0.0001 |
0.0018 |
GO:0016577 |
histone demethylation |
31 |
1.0362 |
6.7555 |
0.0001 |
0.0018 |
GO:0006406 |
mRNA export from nucleus |
108 |
3.6099 |
3.6012 |
0.0001 |
0.002 |
GO:0035278 |
miRNA mediated inhibition of translation |
14 |
0.468 |
10.685 |
0.0001 |
0.002 |
GO:0010647 |
positive regulation of cell communication |
1732 |
57.893 |
1.5028 |
0.0001 |
0.002 |
GO:0070936 |
protein K48-linked ubiquitination |
55 |
1.8384 |
4.8956 |
0.0001 |
0.0023 |
GO:0035194 |
posttranscriptional gene silencing by RNA |
97 |
3.2423 |
3.7011 |
0.0001 |
0.0026 |
GO:0043085 |
positive regulation of catalytic activity |
1380 |
46.127 |
1.5609 |
0.0001 |
0.0028 |
GO:0048024 |
regulation of mRNA splicing, via spliceosome |
98 |
3.2757 |
3.6634 |
0.0001 |
0.0029 |
GO:0071375 |
cellular response to peptide hormone stimulus |
307 |
10.262 |
2.3388 |
0.0001 |
0.003 |
GO:0034329 |
cell junction assembly |
235 |
7.855 |
2.5462 |
0.0001 |
0.0034 |
GO:0006469 |
negative regulation of protein kinase activity |
217 |
7.2533 |
2.6195 |
0.0001 |
0.0034 |
GO:0051081 |
nuclear envelope disassembly |
16 |
0.5348 |
9.3492 |
0.0001 |
0.0035 |
GO:0071345 |
cellular response to cytokine stimulus |
1015 |
33.927 |
1.6506 |
0.0002 |
0.0039 |
GO:2001020 |
regulation of response to DNA damage stimulus |
203 |
6.7853 |
2.6528 |
0.0002 |
0.0042 |
GO:1901992 |
positive regulation of mitotic cell cycle phase transition |
74 |
2.4735 |
4.0429 |
0.0002 |
0.0043 |
GO:0072698 |
protein localization to microtubule cytoskeleton |
48 |
1.6044 |
4.9862 |
0.0002 |
0.0044 |
GO:0120031 |
plasma membrane bounded cell projection assembly |
588 |
19.654 |
1.8826 |
0.0002 |
0.0045 |
GO:0006606 |
protein import into nucleus |
155 |
5.1809 |
2.8952 |
0.0002 |
0.0054 |
GO:1990090 |
cellular response to nerve growth factor stimulus |
50 |
1.6713 |
4.7868 |
0.0002 |
0.0057 |
GO:0050657 |
nucleic acid transport |
191 |
6.3842 |
2.6628 |
0.0002 |
0.0058 |
GO:0006349 |
regulation of gene expression by genetic imprinting |
18 |
0.6017 |
8.3104 |
0.0002 |
0.0059 |
GO:0046700 |
heterocycle catabolic process |
599 |
20.022 |
1.848 |
0.0003 |
0.0061 |
GO:0030183 |
B cell differentiation |
124 |
4.1447 |
3.1365 |
0.0003 |
0.0062 |
GO:0051707 |
response to other organism |
897 |
29.983 |
1.6676 |
0.0003 |
0.0064 |
GO:0031570 |
DNA integrity checkpoint |
158 |
5.2812 |
2.8403 |
0.0003 |
0.0064 |
GO:0006337 |
nucleosome disassembly |
19 |
0.6351 |
7.873 |
0.0003 |
0.0074 |
GO:0006305 |
DNA alkylation |
66 |
2.2061 |
4.0796 |
0.0003 |
0.0075 |
GO:0031295 |
T cell costimulation |
53 |
1.7715 |
4.5158 |
0.0003 |
0.0078 |
GO:2000583 |
regulation of platelet-derived growth factor receptor-alpha signaling pathway |
5 |
0.1671 |
17.95 |
0.0004 |
0.0078 |
GO:1905449 |
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis |
5 |
0.1671 |
17.95 |
0.0004 |
0.0078 |
GO:0001568 |
blood vessel development |
654 |
21.86 |
1.7841 |
0.0004 |
0.0078 |
GO:2000301 |
negative regulation of synaptic vesicle exocytosis |
5 |
0.1671 |
17.95 |
0.0004 |
0.0078 |
GO:0043534 |
blood vessel endothelial cell migration |
112 |
3.7436 |
3.2054 |
0.0004 |
0.0079 |
GO:0044818 |
mitotic G2/M transition checkpoint |
30 |
1.0028 |
5.9835 |
0.0004 |
0.0087 |
GO:0034605 |
cellular response to heat |
98 |
3.2757 |
3.3581 |
0.0004 |
0.009 |
GO:0098813 |
nuclear chromosome segregation |
258 |
8.6237 |
2.3192 |
0.0004 |
0.0092 |
GO:0048511 |
rhythmic process |
279 |
9.3257 |
2.2518 |
0.0005 |
0.0098 |
GO:0007266 |
Rho protein signal transduction |
203 |
6.7853 |
2.5054 |
0.0005 |
0.01 |
GO:0010826 |
negative regulation of centrosome duplication |
12 |
0.4011 |
9.9725 |
0.0005 |
0.0102 |
GO:1901988 |
negative regulation of cell cycle phase transition |
186 |
6.2171 |
2.5735 |
0.0005 |
0.0106 |
GO:0030182 |
neuron differentiation |
1313 |
43.888 |
1.5038 |
0.0005 |
0.0109 |
GO:0045860 |
positive regulation of protein kinase activity |
513 |
17.147 |
1.8662 |
0.0006 |
0.0111 |
GO:0051094 |
positive regulation of developmental process |
1314 |
43.921 |
1.5027 |
0.0006 |
0.0111 |
GO:1903955 |
positive regulation of protein targeting to mitochondrion |
32 |
1.0696 |
5.6095 |
0.0006 |
0.0116 |
GO:0014070 |
response to organic cyclic compound |
905 |
30.25 |
1.6198 |
0.0006 |
0.0117 |
GO:0048193 |
Golgi vesicle transport |
366 |
12.234 |
2.0435 |
0.0006 |
0.0119 |
GO:0000288 |
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
72 |
2.4066 |
3.7397 |
0.0006 |
0.0123 |
GO:0044843 |
cell cycle G1/S phase transition |
247 |
8.2561 |
2.3013 |
0.0007 |
0.0128 |
GO:1905268 |
negative regulation of chromatin organization |
59 |
1.9721 |
4.0566 |
0.0007 |
0.0136 |
GO:0090316 |
positive regulation of intracellular protein transport |
157 |
5.2478 |
2.6678 |
0.0008 |
0.0149 |
GO:0071868 |
cellular response to monoamine stimulus |
34 |
1.1365 |
5.2795 |
0.0008 |
0.0151 |
GO:0016579 |
protein deubiquitination |
272 |
9.0917 |
2.1998 |
0.0009 |
0.0156 |
GO:0051674 |
localization of cell |
1518 |
50.74 |
1.4387 |
0.001 |
0.0171 |
GO:0000723 |
telomere maintenance |
143 |
4.7798 |
2.7198 |
0.001 |
0.0181 |
GO:0042098 |
T cell proliferation |
180 |
6.0166 |
2.4931 |
0.0011 |
0.0189 |
GO:0043254 |
regulation of protein complex assembly |
447 |
14.941 |
1.874 |
0.0011 |
0.0199 |
GO:0046580 |
negative regulation of Ras protein signal transduction |
49 |
1.6378 |
4.2739 |
0.0011 |
0.0199 |
GO:0035304 |
regulation of protein dephosphorylation |
128 |
4.2784 |
2.8048 |
0.0012 |
0.0211 |
GO:0043087 |
regulation of GTPase activity |
472 |
15.777 |
1.8381 |
0.0013 |
0.0217 |
GO:0032479 |
regulation of type I interferon production |
112 |
3.7436 |
2.9383 |
0.0013 |
0.0225 |
GO:0001952 |
regulation of cell-matrix adhesion |
112 |
3.7436 |
2.9383 |
0.0013 |
0.0225 |
GO:0042058 |
regulation of epidermal growth factor receptor signaling pathway |
80 |
2.674 |
3.3657 |
0.0014 |
0.0233 |
GO:0009896 |
positive regulation of catabolic process |
409 |
13.671 |
1.9018 |
0.0014 |
0.0233 |
GO:0051648 |
vesicle localization |
305 |
10.195 |
2.0599 |
0.0015 |
0.0247 |
GO:0045582 |
positive regulation of T cell differentiation |
81 |
2.7075 |
3.3242 |
0.0015 |
0.025 |
GO:0140013 |
meiotic nuclear division |
169 |
5.6489 |
2.4784 |
0.0016 |
0.0266 |
GO:0010970 |
transport along microtubule |
151 |
5.0472 |
2.5757 |
0.0017 |
0.0271 |
GO:0034351 |
negative regulation of glial cell apoptotic process |
8 |
0.2674 |
11.219 |
0.0018 |
0.0287 |
GO:0045089 |
positive regulation of innate immune response |
311 |
10.395 |
2.0201 |
0.0019 |
0.0291 |
GO:0007254 |
JNK cascade |
212 |
7.0862 |
2.2579 |
0.0021 |
0.0319 |
GO:0007155 |
cell adhesion |
1369 |
45.759 |
1.4205 |
0.0025 |
0.0369 |
GO:1901983 |
regulation of protein acetylation |
71 |
2.3732 |
3.371 |
0.0025 |
0.0369 |
GO:0043902 |
positive regulation of multi-organism process |
158 |
5.2812 |
2.4616 |
0.0025 |
0.0372 |
GO:0000245 |
spliceosomal complex assembly |
56 |
1.8718 |
3.7397 |
0.0025 |
0.0372 |
GO:0038155 |
interleukin-23-mediated signaling pathway |
9 |
0.3008 |
9.9725 |
0.0027 |
0.0392 |
GO:0042127 |
regulation of cell proliferation |
1564 |
52.277 |
1.3773 |
0.0032 |
0.0454 |
GO:0039529 |
RIG-I signaling pathway |
19 |
0.6351 |
6.2984 |
0.0032 |
0.0456 |
GO:0070303 |
negative regulation of stress-activated protein kinase signaling cascade |
44 |
1.4707 |
4.0796 |
0.0033 |
0.046 |
GO:0030218 |
erythrocyte differentiation |
109 |
3.6434 |
2.7447 |
0.0035 |
0.0489 |