Pathway name | Network | Gene having VISes | Other gene | Definition | Expanded | Disease |
---|
Gene set | Description | Size | Expect | Ratio | PValue | FDR |
---|---|---|---|---|---|---|
GO:0000902 | cell morphogenesis | 982 | 33.472 | 2.6589 | 0 | 0 |
GO:0000904 | cell morphogenesis involved in differentiation | 714 | 24.337 | 2.9585 | 1.11E-16 | 5.94E-14 |
GO:0001764 | neuron migration | 151 | 5.1469 | 3.1087 | 0.0001 | 0.0037 |
GO:0001964 | startle response | 28 | 0.9544 | 6.2867 | 0.0003 | 0.0144 |
GO:0006928 | movement of cell or subcellular component | 1967 | 67.046 | 1.7451 | 7.58E-10 | 1.68E-7 |
GO:0007155 | cell adhesion | 1369 | 46.663 | 2.3573 | 0 | 0 |
GO:0007264 | small GTPase mediated signal transduction | 552 | 18.815 | 2.1259 | 6.1799E-6 | 0.0006 |
GO:0007267 | cell-cell signaling | 1575 | 53.685 | 1.7882 | 1.08E-8 | 1.8935E-6 |
GO:0007268 | chemical synaptic transmission | 685 | 23.349 | 2.2699 | 2.16E-8 | 3.2122E-6 |
GO:0007409 | axonogenesis | 449 | 15.304 | 3.2017 | 5.58E-13 | 1.75E-10 |
GO:0007411 | axon guidance | 259 | 8.8281 | 3.9646 | 3.21E-12 | 9.42E-10 |
GO:0007416 | synapse assembly | 164 | 5.59 | 5.1878 | 2.58E-13 | 9.38E-11 |
GO:0007417 | central nervous system development | 949 | 32.347 | 2.164 | 7.58E-10 | 1.68E-7 |
GO:0007420 | brain development | 714 | 24.337 | 2.1367 | 2.05E-7 | 0 |
GO:0007611 | learning or memory | 244 | 8.3169 | 2.2845 | 0.0007 | 0.0287 |
GO:0008016 | regulation of heart contraction | 205 | 6.9875 | 2.4329 | 0.0007 | 0.0271 |
GO:0008038 | neuron recognition | 47 | 1.602 | 8.739 | 2.95E-10 | 7.46E-8 |
GO:0010769 | regulation of cell morphogenesis involved in differentiation | 293 | 9.987 | 3.5045 | 1.09E-10 | 2.92E-8 |
GO:0010810 | regulation of cell-substrate adhesion | 203 | 6.9193 | 2.8904 | 0 | 0.0016 |
GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 24 | 0.8181 | 7.3345 | 0.0001 | 0.0066 |
GO:0010975 | regulation of neuron projection development | 475 | 16.191 | 3.397 | 1.55E-15 | 7.07E-13 |
GO:0010977 | negative regulation of neuron projection development | 148 | 5.0446 | 3.3699 | 0 | 0.001 |
GO:0016055 | Wnt signaling pathway | 456 | 15.543 | 1.9301 | 0.0005 | 0.0205 |
GO:0016358 | dendrite development | 219 | 7.4647 | 3.8849 | 3.92E-10 | 9.37E-8 |
GO:0019722 | calcium-mediated signaling | 214 | 7.2943 | 2.6048 | 0.0001 | 0.0074 |
Gene set | Description | Size | Expect | Ratio | PValue | FDR |
---|---|---|---|---|---|---|
GO:0004714 | transmembrane receptor protein tyrosine kinase activity | 64 | 2.012 | 4.4732 | 0.0002 | 0.009 |
GO:0004970 | ionotropic glutamate receptor activity | 19 | 0.5973 | 8.3708 | 0.0002 | 0.0117 |
GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity | 17 | 0.5344 | 9.3556 | 0.0001 | 0.008 |
GO:0005003 | ephrin receptor activity | 19 | 0.5973 | 8.3708 | 0.0002 | 0.0117 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 329 | 10.343 | 3.4806 | 7.44E-11 | 1.4E-7 |
GO:0005088 | Ras guanyl-nucleotide exchange factor activity | 255 | 8.0166 | 3.6175 | 2.23E-9 | 2.0905E-6 |
GO:0005089 | Rho guanyl-nucleotide exchange factor activity | 80 | 2.515 | 4.7714 | 7.0746E-6 | 0.0006 |
GO:0005096 | GTPase activator activity | 275 | 8.6453 | 3.2388 | 4.79E-8 | 0 |
GO:0005215 | transporter activity | 1235 | 38.825 | 1.5196 | 0.0008 | 0.0287 |
GO:0005216 | ion channel activity | 415 | 13.047 | 2.5294 | 1.0617E-6 | 0.0002 |
GO:0005261 | cation channel activity | 318 | 9.9971 | 2.5007 | 0 | 0.0019 |
GO:0005509 | calcium ion binding | 687 | 21.598 | 2.0836 | 2.7223E-6 | 0.0003 |
GO:0005543 | phospholipid binding | 412 | 12.952 | 2.3934 | 7.0058E-6 | 0.0006 |
GO:0008047 | enzyme activator activity | 519 | 16.316 | 2.4516 | 1.72E-7 | 0 |
GO:0008066 | glutamate receptor activity | 27 | 0.8488 | 9.4249 | 1.1848E-6 | 0.0002 |
GO:0008092 | cytoskeletal protein binding | 940 | 29.551 | 1.8612 | 6.4235E-6 | 0.0006 |
GO:0015075 | ion transmembrane transporter activity | 882 | 27.728 | 1.695 | 0.0003 | 0.0128 |
GO:0015085 | calcium ion transmembrane transporter activity | 137 | 4.3069 | 3.0184 | 0.0004 | 0.0167 |
GO:0015267 | channel activity | 456 | 14.335 | 2.3717 | 3.0754E-6 | 0.0003 |
GO:0015276 | ligand-gated ion channel activity | 139 | 4.3698 | 3.2038 | 0.0001 | 0.008 |
GO:0016247 | channel regulator activity | 139 | 4.3698 | 2.7461 | 0.0015 | 0.0431 |
GO:0017016 | Ras GTPase binding | 534 | 16.788 | 2.5614 | 1.64E-8 | 7.7185E-6 |
GO:0017048 | Rho GTPase binding | 175 | 5.5016 | 3.09 | 0 | 0.0027 |
GO:0017124 | SH3 domain binding | 126 | 3.9611 | 3.2819 | 0.0002 | 0.009 |
GO:0019198 | transmembrane receptor protein phosphatase activity | 17 | 0.5344 | 9.3556 | 0.0001 | 0.008 |
VIS ID | Virus genome | Human genome | Target gene | Sample | Disease | Method | PubMed ID | Curated way | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Virus Name | Subtype | Reference | Start | End | Chromosome | Loci | Reference | Start | End |