Virus pathway
Virus pathway diagram
Pathway name Network Gene having VISes Other gene Definition Expanded Disease
GO summary
Enrichment results
BP table
Gene set Description Size Expect Ratio PValue FDR
GO:0048813 dendrite morphogenesis 137 4.6697 4.0688 2.03E-7 0
GO:0022008 neurogenesis 1551 52.867 2.4779 0 0
GO:0120036 plasma membrane bounded cell projection organization 1488 50.719 2.2674 0 0
GO:0048699 generation of neurons 1454 49.56 2.5625 0 0
GO:0022610 biological adhesion 1377 46.936 2.3436 0 0
GO:0007155 cell adhesion 1369 46.663 2.3573 0 0
GO:0030182 neuron differentiation 1313 44.754 2.726 0 0
GO:0032989 cellular component morphogenesis 1082 36.88 2.5759 0 0
GO:0048666 neuron development 1068 36.403 2.9393 0 0
GO:0000902 cell morphogenesis 982 33.472 2.6589 0 0
GO:0031175 neuron projection development 940 32.04 2.8402 0 0
GO:0032990 cell part morphogenesis 656 22.36 3.3095 0 0
GO:0048858 cell projection morphogenesis 637 21.712 3.3161 0 0
GO:0120039 plasma membrane bounded cell projection morphogenesis 636 21.678 3.3213 0 0
GO:0048812 neuron projection morphogenesis 622 21.201 3.3489 0 0
GO:0048667 cell morphogenesis involved in neuron differentiation 560 19.088 3.4053 0 0
GO:0007420 brain development 714 24.337 2.1367 2.05E-7 0
GO:0030030 cell projection organization 1522 51.878 2.236 0 0
GO:0000904 cell morphogenesis involved in differentiation 714 24.337 2.9585 1.11E-16 5.94E-14
GO:0051960 regulation of nervous system development 879 29.961 2.6701 5.55E-16 2.8E-13
GO:0045664 regulation of neuron differentiation 628 21.406 3.0366 8.88E-16 4.25E-13
GO:0010975 regulation of neuron projection development 475 16.191 3.397 1.55E-15 7.07E-13
GO:0120035 regulation of plasma membrane bounded cell projection organization 665 22.667 2.9117 4.22E-15 1.83E-12
GO:0031344 regulation of cell projection organization 674 22.974 2.8729 8.22E-15 3.39E-12
GO:0050767 regulation of neurogenesis 776 26.45 2.6843 2.26E-14 8.95E-12
GO:0060284 regulation of cell development 895 30.506 2.4913 1.26E-13 4.77E-11
GO:0007416 synapse assembly 164 5.59 5.1878 2.58E-13 9.38E-11
GO:0043087 regulation of GTPase activity 472 16.088 3.17 2.69E-13 9.41E-11
GO:0050808 synapse organization 385 13.123 3.4291 4.67E-13 1.57E-10
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 270 9.2031 4.0204 4.92E-13 1.6E-10
GO:0007409 axonogenesis 449 15.304 3.2017 5.58E-13 1.75E-10
GO:0061564 axon development 490 16.702 3.0535 1.14E-12 3.47E-10
GO:0007411 axon guidance 259 8.8281 3.9646 3.21E-12 9.42E-10
GO:0097485 neuron projection guidance 260 8.8622 3.9493 3.6E-12 1.02E-9
GO:0051962 positive regulation of nervous system development 512 17.452 2.865 2.03E-11 5.6E-9
GO:0010769 regulation of cell morphogenesis involved in differentiation 293 9.987 3.5045 1.09E-10 2.92E-8
GO:0045595 regulation of cell differentiation 1699 57.911 1.8477 1.94E-10 5.03E-8
GO:0008038 neuron recognition 47 1.602 8.739 2.95E-10 7.46E-8
GO:0043547 positive regulation of GTPase activity 400 13.634 3.0071 3.3E-10 8.1E-8
GO:0016358 dendrite development 219 7.4647 3.8849 3.92E-10 9.37E-8
GO:0098609 cell-cell adhesion 807 27.507 2.2903 6.29E-10 1.47E-7
GO:0006928 movement of cell or subcellular component 1967 67.046 1.7451 7.58E-10 1.68E-7
GO:0007417 central nervous system development 949 32.347 2.164 7.58E-10 1.68E-7
GO:0050769 positive regulation of neurogenesis 447 15.236 2.691 8.84E-9 1.5756E-6
GO:0007267 cell-cell signaling 1575 53.685 1.7882 1.08E-8 1.8935E-6
GO:0048588 developmental cell growth 213 7.2602 3.5812 1.8E-8 2.769E-6
GO:0007268 chemical synaptic transmission 685 23.349 2.2699 2.16E-8 3.2122E-6
GO:0030334 regulation of cell migration 804 27.405 2.007 6.71E-7 0.0001
GO:0050768 negative regulation of neurogenesis 278 9.4758 2.8494 1.0606E-6 0.0001
GO:0050807 regulation of synapse organization 215 7.3284 3.1385 1.279E-6 0.0001
GO:0035249 synaptic transmission, glutamatergic 90 3.0677 4.5637 2.028E-6 0.0002
GO:0061387 regulation of extent of cell growth 105 3.579 4.1911 2.6551E-6 0.0003
GO:0051056 regulation of small GTPase mediated signal transduction 331 11.282 2.5704 3.4478E-6 0.0003
GO:0034330 cell junction organization 285 9.7144 2.6765 5.328E-6 0.0005
GO:0098698 postsynaptic specialization assembly 22 0.7499 9.3348 5.6234E-6 0.0005
GO:0007264 small GTPase mediated signal transduction 552 18.815 2.1259 6.1799E-6 0.0006
GO:0097120 receptor localization to synapse 51 1.7384 5.7526 7.0863E-6 0.0006
GO:0051345 positive regulation of hydrolase activity 746 25.428 1.927 8.5612E-6 0.0007
GO:0051674 localization of cell 1518 51.742 1.6041 9.9972E-6 0.0008
GO:0010977 negative regulation of neuron projection development 148 5.0446 3.3699 0 0.001
GO:0030336 negative regulation of cell migration 252 8.5895 2.6777 0 0.0014
GO:0010810 regulation of cell-substrate adhesion 203 6.9193 2.8904 0 0.0016
GO:0030029 actin filament-based process 715 24.371 1.8875 0 0.0019
GO:0099151 regulation of postsynaptic density assembly 12 0.409 12.224 0 0.002
GO:1905606 regulation of presynapse assembly 29 0.9885 7.0816 0 0.0028
GO:0001764 neuron migration 151 5.1469 3.1087 0.0001 0.0037
GO:0060997 dendritic spine morphogenesis 54 1.8406 4.8897 0.0001 0.0047
GO:0032412 regulation of ion transmembrane transporter activity 228 7.7715 2.5735 0.0001 0.0061
GO:0044087 regulation of cellular component biogenesis 940 32.04 1.6854 0.0001 0.0065
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 24 0.8181 7.3345 0.0001 0.0066
GO:0019722 calcium-mediated signaling 214 7.2943 2.6048 0.0001 0.0074
GO:0021952 central nervous system projection neuron axonogenesis 25 0.8521 7.0411 0.0002 0.0082
GO:0030010 establishment of cell polarity 132 4.4993 3.1116 0.0002 0.0086
GO:1900449 regulation of glutamate receptor signaling pathway 48 1.6361 4.8897 0.0002 0.01
GO:2000171 negative regulation of dendrite development 26 0.8862 6.7703 0.0002 0.01
GO:0048846 axon extension involved in axon guidance 37 1.2612 5.5504 0.0002 0.0108
GO:0098655 cation transmembrane transport 810 27.609 1.7023 0.0003 0.0128
GO:0086003 cardiac muscle cell contraction 63 2.1474 4.1911 0.0003 0.0129
GO:0001964 startle response 28 0.9544 6.2867 0.0003 0.0144
GO:0051703 intraspecies interaction between organisms 54 1.8406 4.3464 0.0005 0.02
GO:0016055 Wnt signaling pathway 456 15.543 1.9301 0.0005 0.0205
GO:2000114 regulation of establishment of cell polarity 21 0.7158 6.9852 0.0006 0.024
GO:0008016 regulation of heart contraction 205 6.9875 2.4329 0.0007 0.0271
GO:0007611 learning or memory 244 8.3169 2.2845 0.0007 0.0287
GO:0045927 positive regulation of growth 250 8.5214 2.2297 0.001 0.0367
GO:0099565 chemical synaptic transmission, postsynaptic 107 3.6471 3.0161 0.0011 0.0391
GO:0035385 Roundabout signaling pathway 7 0.2386 12.573 0.0012 0.0456
MF table
Gene set Description Size Expect Ratio PValue FDR
GO:0008047 enzyme activator activity 519 16.316 2.4516 1.72E-7 0
GO:0031267 small GTPase binding 551 17.322 2.4824 4.07E-8 0
GO:0005096 GTPase activator activity 275 8.6453 3.2388 4.79E-8 0
GO:0030695 GTPase regulator activity 305 9.5884 3.0245 1.23E-7 0
GO:0005085 guanyl-nucleotide exchange factor activity 329 10.343 3.4806 7.44E-11 1.4E-7
GO:0005088 Ras guanyl-nucleotide exchange factor activity 255 8.0166 3.6175 2.23E-9 2.0905E-6
GO:0051020 GTPase binding 646 20.309 2.4128 1.1E-8 6.8725E-6
GO:0017016 Ras GTPase binding 534 16.788 2.5614 1.64E-8 7.7185E-6
GO:0098772 molecular function regulator 1843 57.939 1.6396 7.01E-7 0.0001
GO:0022838 substrate-specific channel activity 431 13.55 2.5093 8.73E-7 0.0001
GO:0060589 nucleoside-triphosphatase regulator activity 348 10.94 2.7422 6.21E-7 0.0001
GO:0008066 glutamate receptor activity 27 0.8488 9.4249 1.1848E-6 0.0002
GO:0022836 gated channel activity 344 10.815 2.6816 1.5057E-6 0.0002
GO:0005216 ion channel activity 415 13.047 2.5294 1.0617E-6 0.0002
GO:0022839 ion gated channel activity 335 10.532 2.6587 2.6972E-6 0.0003
GO:0015267 channel activity 456 14.335 2.3717 3.0754E-6 0.0003
GO:0022803 passive transmembrane transporter activity 457 14.367 2.3665 3.2267E-6 0.0003
GO:0005509 calcium ion binding 687 21.598 2.0836 2.7223E-6 0.0003
GO:0008092 cytoskeletal protein binding 940 29.551 1.8612 6.4235E-6 0.0006
GO:0005543 phospholipid binding 412 12.952 2.3934 7.0058E-6 0.0006
GO:0005089 Rho guanyl-nucleotide exchange factor activity 80 2.515 4.7714 7.0746E-6 0.0006
GO:0030546 receptor activator activity 11 0.3458 14.459 0 0.001
GO:0045499 chemorepellent activity 27 0.8488 8.2468 0 0.0012
GO:0035091 phosphatidylinositol binding 236 7.4192 2.8305 0 0.0015
GO:0050839 cell adhesion molecule binding 478 15.027 2.196 0 0.0016
GO:0005261 cation channel activity 318 9.9971 2.5007 0 0.0019
GO:0017048 Rho GTPase binding 175 5.5016 3.09 0 0.0027
GO:0015276 ligand-gated ion channel activity 139 4.3698 3.2038 0.0001 0.008
GO:0022834 ligand-gated channel activity 139 4.3698 3.2038 0.0001 0.008
GO:0030676 Rac guanyl-nucleotide exchange factor activity 17 0.5344 9.3556 0.0001 0.008
GO:0019198 transmembrane receptor protein phosphatase activity 17 0.5344 9.3556 0.0001 0.008
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 17 0.5344 9.3556 0.0001 0.008
GO:0098632 cell-cell adhesion mediator activity 50 1.5719 5.0895 0.0002 0.0086
GO:0004714 transmembrane receptor protein tyrosine kinase activity 64 2.012 4.4732 0.0002 0.009
GO:0017124 SH3 domain binding 126 3.9611 3.2819 0.0002 0.009
GO:0030234 enzyme regulator activity 1017 31.972 1.6577 0.0002 0.0106
GO:0032559 adenyl ribonucleotide binding 1509 47.439 1.5177 0.0002 0.0112
GO:0004970 ionotropic glutamate receptor activity 19 0.5973 8.3708 0.0002 0.0117
GO:0005003 ephrin receptor activity 19 0.5973 8.3708 0.0002 0.0117
GO:1901981 phosphatidylinositol phosphate binding 150 4.7156 2.9689 0.0003 0.0128
GO:0015075 ion transmembrane transporter activity 882 27.728 1.695 0.0003 0.0128
GO:0015085 calcium ion transmembrane transporter activity 137 4.3069 3.0184 0.0004 0.0167
GO:0022835 transmitter-gated channel activity 61 1.9177 4.1717 0.0006 0.0231
GO:0005215 transporter activity 1235 38.825 1.5196 0.0008 0.0287
GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 7 0.2201 13.633 0.001 0.0313
GO:0016247 channel regulator activity 139 4.3698 2.7461 0.0015 0.0431
GO:0042578 phosphoric ester hydrolase activity 370 11.632 1.9773 0.0015 0.0437