hsa-mir-3691-3p _LIHC.png
CORO2A _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000001
Fusion event
HBV-CORO2A integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2019
PubMed ID
30535432
Virus Sequence
Virus name
HBV
Reference genome
FJ562281.1
Region type
X
Start
1782
Integrated sequence
TCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAATGATCTTTGTACTAGGAGGCT| |GTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGC
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
100940295/98178013 (Hg38)
End
100940295/98178013 (Hg38)
Location type
Intronic
Target gene
CORO2A
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-21-5p ; hsa-mir-6778-3p ; hsa-mir-6128 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-3691-3p ; hsa-mir-4279 ; hsa-mir-8081 ; hsa-mir-1231 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-516b-5p ; hsa-mir-7977 ; hsa-mir-3120-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-4267 ; hsa-mir-6736-3p ; hsa-mir-5588-3p ; hsa-mir-29b-2-5p ; hsa-mir-3187-3p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-4755-3p ; hsa-mir-29b-1-5p ; hsa-mir-4507 ; hsa-mir-3940-5p
Nearest miRNA
hsa-let-7a-1/Upstream/814332; hsa-mir-12126/Downstream/51136;
Nearest TSS
ENST00000422679/Upstream/5129; ENST00000610463/Downstream/14627;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/58635, chr9-CpG: 24/Downstream/13991
Downstream sequence
GCTCTCTCACTTTTTTTCTTTTTTAAATTTATTTTTATTAAAAACATTTTTTTAGAGACAGAGTCTCGCTCTGTCACCTAGGCTGGAGTGCAGTGGTGCCATCATAA
Junction sequence
ACGCCACTGGAACCTGCCCAAGGTCTTACATAAAAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAATGATCTTTGTACTAGGAGGCTCTCTCACTTTTTTTCTTTTTTAAATTTATTTTTATTAAAAACATTTTTTTAGAGACAGAGTCTCGCTCTGTCACCTAGGCTGGAGTGCAGTGGTGCCATCATAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ruan, P., et al. Different types of viralhost junction found in HBV integration breakpoints in HBVinfected patients. Mol Med Rep ,2019,19(2): 1410-1416.
Curate