Basic Information
VIS ID
TVIS10000002
Fusion event
HBV-chr9:q22.33 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
PreC/X
Start
1820
Integrated sequence
GTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTAGGGCATGGACATTGACCCGTATAA
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
End
101030026/98267744 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-1/Upstream/38527; hsa-mir-12126/Downstream/8333184;
Downstream sequence
GAAACCTAGCTGACCCCATAGATCCTAAATCCTTTCCCCACTCCTTTCTGTTCCCTGAAGACAACTTTAGAGACTGCCCCCACCCTAGATCTCCCTGAATGATCCCCACCA
Junction sequence
AGAGGTGAAAAAGGAAACCTAGCTGACCCCATAGATCCTAAATCCTTTCCCCACTCCTTTCTGTTCCCTGAAGACAACTTTAGAGACTGCCCCCACCCTAGATCTCCCTGAATGATCCCCACCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ruan, P., et al. Different types of viralhost junction found in HBV integration breakpoints in HBVinfected patients. Mol Med Rep ,2019,19(2): 1410-1416.
Curate