Fusion event
HBV-chr9:q22.33 integration
Detection method
PCR and Sanger sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Integrated sequence
GTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTAGGGCATGGACATTGACCCGTATAA
End
101030026/98267744 (Hg38)
Nearest miRNA
hsa-let-7a-1/Upstream/38527; hsa-mir-12126/Downstream/8333184;
Downstream sequence
GAAACCTAGCTGACCCCATAGATCCTAAATCCTTTCCCCACTCCTTTCTGTTCCCTGAAGACAACTTTAGAGACTGCCCCCACCCTAGATCTCCCTGAATGATCCCCACCA
Junction sequence
AGAGGTGAAAAAGGAAACCTAGCTGACCCCATAGATCCTAAATCCTTTCCCCACTCCTTTCTGTTCCCTGAAGACAACTTTAGAGACTGCCCCCACCCTAGATCTCCCTGAATGATCCCCACCA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Ruan, P., et al. Different types of viralhost junction found in HBV integration breakpoints in HBVinfected patients. Mol Med Rep ,2019,19(2): 1410-1416.