Basic Information
VIS ID
TVIS10000003
Fusion event
HBV-chr3:p26.3 integraiton
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2019
PubMed ID
30535432
Virus Sequence
Virus name
HBV
Reference genome
KC792890.1
Region type
P/X
Start
1471
Integrated sequence
ctaggctgcgctgccaactggatcctacgcgggacgtcctttgttcacgtcccgtcagcgctcaatcccgcggacgacccctcccgg| |ggccgtttggggctctaccgcccccttctccgtctgccgttccagccgacaacgggtcgcacctctctttacgcggtctccccgtctgtgcct
Host Sequence
Chromosome
chr3
Cytoband
p26.3
Reference genome
GRCh37/hg19
Start
2002381/1960697 (Hg38)
End
2002381/1960697 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Downstream/3289480;
Nearest TSS
ENST00000440867/Upstream/559412; ENST00000490876/Downstream/26773;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1651487, chr3-CpG: 182/Downstream/137648
Downstream sequence
CTCCTGGCGCCTCATGATCCCCCAACTCAAACATATTCCTCTGCCAAAACCAGTCGCGTCCTGCCTGGTGG
Junction sequence
CACAAGGGCTCAATCCCGTGAACGACCCCTCCTGGCGCCTCATGATCCCCCAACTCAAACATATTCCTCTGCCAAAACCAGTCGCGTCCTGCCTGGTGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ruan, P., et al. Different types of viralhost junction found in HBV integration breakpoints in HBVinfected patients. Mol Med Rep ,2019,19(2): 1410-1416.
Curate