Basic Information
VIS ID
TVIS10000053
Fusion event
HBV-LINC00922 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1828
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh38.p7
Start
65449145 (Hg38)
End
65449145 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC00922
Nearest miRNA
hsa-mir-1225/Upstream/7676793; hsa-mir-11401/Downstream/1753176;
Nearest TSS
ENST00000527434/Upstream/214231; ENST00000563811/Downstream/122644;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/325384, chr16-CpG: 40/Downstream/821237
Downstream sequence
GTCTGCGCTTCTCCACCCTGCAACTTGTTC
Junction sequence
GCTGTGTGCATAAATTGGTCTGCGCTTCTGTCTGCGCTTCTCCACCCTGCAACTTGTTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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