VISDB Viral Integration Site DataBase

VIS ID

TVIS10000059

Fusion event

HBV-ACACA integration

Validated

Yes

Detection method

invPCR

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

End

1835

Integrated sequence

GAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG| |CCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCT

Chromosome

chr17

Cytoband

q12

Reference genome

Start

End

37327350 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-193b-3p ; hsa-mir-339-5p ; hsa-mir-324-3p ; hsa-mir-222-3p ; hsa-mir-92a-3p ; hsa-mir-142-3p ; hsa-mir-218-5p ; hsa-mir-4646-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-491-3p ; hsa-mir-4433b-5p ; hsa-mir-1269b ; hsa-mir-1269a ; hsa-mir-580-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4515 ; hsa-mir-1288-3p ; hsa-mir-4740-5p ; hsa-mir-6857-3p ; hsa-mir-219a-2-3p ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4251 ; hsa-mir-4254 ; hsa-mir-3690 ; hsa-mir-361-3p ; hsa-mir-1250-3p ; hsa-mir-1255b-2-3p ; hsa-mir-1207-5p ; hsa-mir-1282 ; hsa-mir-182-3p ; hsa-mir-211-3p ; hsa-mir-3125 ; hsa-mir-3916 ; hsa-mir-4261 ; hsa-mir-4436b-3p ; hsa-mir-4496 ; hsa-mir-4632-5p ; hsa-mir-4636 ; hsa-mir-4763-3p ; hsa-mir-4777-5p ; hsa-mir-494-3p ; hsa-mir-5002-5p ; hsa-mir-5010-3p ; hsa-mir-5095 ; hsa-mir-518d-5p ; hsa-mir-518e-5p ; hsa-mir-518f-5p ; hsa-mir-519a-5p ; hsa-mir-519b-5p ; hsa-mir-519c-5p ; hsa-mir-520c-5p ; hsa-mir-520g-5p ; hsa-mir-522-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-541-3p ; hsa-mir-5707 ; hsa-mir-592 ; hsa-mir-597-5p ; hsa-mir-654-5p ; hsa-mir-6721-5p ; hsa-mir-6735-5p ; hsa-mir-6758-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6823-5p ; hsa-mir-6856-5p ; hsa-mir-6859-5p ; hsa-mir-6879-5p ; hsa-mir-7151-3p ; hsa-mir-7843-5p ; hsa-mir-7845-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-1180/Upstream/293537; hsa-mir-10226/Downstream/287581;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/377893, chr17-CpG: 76/Downstream/31503

Downstream sequence

CACCAGCACCATGCAACTTTTTCACTTCTG

Junction sequence