VISDB Viral Integration Site DataBase

VIS ID

TVIS10000075

Fusion event

HBV-NAV1 integration

Validated

Yes

Detection method

invPCR

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

End

1797

Integrated sequence

TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT| |GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

201619049 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-7-5p ; hsa-mir-218-5p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-6734-5p ; hsa-mir-4316 ; hsa-mir-1294 ; hsa-mir-486-3p ; hsa-mir-3619-3p ; hsa-mir-3140-3p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6743-5p ; hsa-mir-3940-3p ; hsa-mir-4688 ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-924 ; hsa-mir-3691-3p ; hsa-mir-574-5p ; hsa-mir-552-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-580-5p ; hsa-mir-3682-5p ; hsa-mir-5581-3p ; hsa-mir-6780b-3p ; hsa-mir-3166 ; hsa-mir-3913-3p ; hsa-mir-6767-5p ; hsa-mir-8485 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7150 ; hsa-mir-7977 ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7974 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-4728-5p ; hsa-mir-3665 ; hsa-mir-125a-3p ; hsa-mir-383-3p ; hsa-mir-6756-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-4279 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6749-3p ; hsa-mir-452-3p ; hsa-mir-2117 ; hsa-mir-26b-3p ; hsa-mir-4469 ; hsa-mir-1266-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-1470 ; hsa-mir-4667-3p ; hsa-mir-4474-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4777-3p ; hsa-mir-483-5p ; hsa-mir-4681 ; hsa-mir-8084 ; hsa-mir-5003-3p

Nearest miRNA

hsa-mir-101-1/Upstream/2759896; hsa-mir-1182/Downstream/100459;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/78860, chr1-CpG: 186/Downstream/28864

Nearby gene

PRPF31(-85441) ; NAV1(+3836) ;

Downstream sequence

CTTTGTACTAGGAGGCTGTAGGCATAAATT

Junction sequence