hsa-mir-6826-3p _LIHC.png
hsa-mir-5003-5p _LIHC.png
RANBP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000095
Fusion event
HBV-RANBP2 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1813
Integrated sequence
AGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCA| |CCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGA
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh38.p7
Start
109032342 (Hg38)
End
109032342 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
RANBP2
miRNAs that regulate target gene
hsa-mir-708-5p ; hsa-mir-106b-3p ; hsa-mir-421 ; hsa-mir-423-3p ; hsa-mir-186-5p ; hsa-mir-125b-5p ; hsa-let-7g-5p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-539-5p ; hsa-mir-3124-3p ; hsa-mir-3140-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-551b-5p ; hsa-mir-6507-3p ; hsa-mir-4311 ; hsa-mir-4439 ; hsa-mir-943 ; hsa-mir-6826-3p ; hsa-mir-3136-5p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-5003-5p ; hsa-mir-542-3p ; hsa-mir-4504 ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-4501 ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-mir-1285-2/Upstream/6599976; hsa-mir-10b/Downstream/109148;
Nearest TSS
ENST00000437798/Upstream/42970; ENST00000309415/Downstream/96588;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/568, chr2-CpG: 227/Downstream/95787
Nearby gene
EDAR(-42970) ;
Downstream sequence
AGACAGAAGAAAAGGGTTAGAACTTTAGAA
Junction sequence
TGTAGGCATAAATTGGTCTGCGCACCAGCAAGACAGAAGAAAAGGGTTAGAACTTTAGAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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