SPAG16 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000103
Fusion event
HBV-SPAG16 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1719
Integrated sequence
CCGTGAACGCCCACCGAATGTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCTGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTG| |TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC
Host Sequence
Chromosome
chr2
Cytoband
q34
Reference genome
GRCh38.p7
Start
214372366 (Hg38)
End
214372366 (Hg38)
Orient
-
Location type
Intronic
Target gene
SPAG16
miRNAs that regulate target gene
hsa-mir-4713-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-6507-3p ; hsa-mir-6828-5p ; hsa-mir-651-3p ; hsa-mir-3662
Nearest miRNA
hsa-mir-10b/Upstream/614207; hsa-mir-1244-1/Downstream/3528147;
Nearest TSS
ENST00000437798/Upstream/448503; ENST00000477752/Downstream/38699;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1087664, chr2-CpG: 110/Downstream/436905
Downstream sequence
GACCGACCTTGAGGCATACTTCAAAGACTG
Junction sequence
TGATAGAGACTTGTTTCTTACACTGGCATGGACCGACCTTGAGGCATACTTCAAAGACTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate