Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000106
Fusion event
HBV-ITPR1 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
End
1804
Integrated sequence
ATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC| |GCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCAT
Host Sequence
Chromosome
chr3
Cytoband
p26.1
Reference genome
Start
End
4726175 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-424-5p ; hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-128-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-4328 ; hsa-mir-4803 ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-494-3p ; hsa-mir-34c-5p ; hsa-mir-34b-3p ; hsa-mir-449a ; hsa-mir-448 ; hsa-mir-3163
Nearest miRNA
hsa-let-7g/Downstream/524002;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/232492, chr3-CpG: 67/Downstream/142103
Downstream sequence
TGCCTGTAATCCCACCTACCCGGCCGGCTG
Junction sequence
CTAGGAGGCCGTAGGCATAAATTGGTCTGCTGCCTGTAATCCCACCTACCCGGCCGGCTG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).