GRM7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000107
Fusion event
HBV-GRM7 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1786
Integrated sequence
AACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGT| |AGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCT
Host Sequence
Chromosome
chr3
Cytoband
p26.1
Reference genome
GRCh38.p7
Start
6981194 (Hg38)
End
6981194 (Hg38)
Orient
-
Location type
Intronic
Target gene
GRM7
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-34c-5p
Nearest miRNA
hsa-mir-4790/Upstream/1730939; hsa-let-7g/Downstream/3299157;
Nearest TSS
ENST00000440867/Upstream/87172; ENST00000461677/Downstream/317383;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/118240, chr3-CpG: 42/Downstream/1520321
Downstream sequence
AGATTAAAGGTCTTTGTACTAGGAGGCTGT
Junction sequence
TTTAAGTATCAAAAAGATGCAACCCAGAAAAGATTAAAGGTCTTTGTACTAGGAGGCTGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate