VISDB Viral Integration Site DataBase

VIS ID

TVIS10000118

Fusion event

HBV-MBNL1 integration

Validated

Yes

Detection method

invPCR

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

End

1794

Integrated sequence

ACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAA| |ATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGC

Chromosome

chr3

Cytoband

q25.2

Reference genome

Start

End

152361988 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-21-5p ; hsa-mir-19b-3p ; hsa-mir-92b-3p ; hsa-mir-221-3p ; hsa-mir-92a-3p ; hsa-mir-17-5p ; hsa-mir-513a-3p ; hsa-mir-576-5p ; hsa-mir-590-3p ; hsa-mir-936 ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-491-3p ; hsa-mir-590-5p ; hsa-mir-1301-3p ; hsa-mir-4660 ; hsa-mir-5047 ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-let-7f-2-3p ; hsa-mir-19a-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-548aw ; hsa-mir-153-5p ; hsa-mir-552-5p ; hsa-mir-3161 ; hsa-mir-138-2-3p ; hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-629-3p ; hsa-mir-4713-5p ; hsa-mir-4714-3p ; hsa-mir-4775 ; hsa-mir-6867-3p ; hsa-mir-101-3p ; hsa-mir-203a-3p ; hsa-mir-4694-3p ; hsa-mir-218-5p ; hsa-mir-144-3p ; hsa-mir-219a-5p ; hsa-mir-508-3p ; hsa-mir-4445-5p ; hsa-mir-4782-3p ; hsa-mir-6766-3p ; hsa-mir-4482-3p ; hsa-mir-628-5p ; hsa-mir-8075 ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-520d-3p ; hsa-mir-302d-3p ; hsa-mir-302e ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520e ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-302a-3p ; hsa-mir-8064 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4693-5p ; hsa-mir-4711-3p ; hsa-mir-4330 ; hsa-mir-6832-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-5680 ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-5197-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-3591-5p ; hsa-mir-374b-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3124-3p ; hsa-mir-877-3p ; hsa-mir-6760-3p ; hsa-mir-889-5p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-5583-3p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-580-3p ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-500a-5p ; hsa-mir-10b-5p

Nearest miRNA

hsa-let-7g/Upstream/795993; hsa-mir-1224/Downstream/6920658;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/92452, chr3-CpG: 120/Downstream/472825

Downstream sequence

GGTCTTTGTACTAGGAGGCTGTAGGCATAA

Junction sequence