Basic Information
VIS ID
TVIS10000140
Fusion event
HBV-LINC02147 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1829
Integrated sequence
GACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
GRCh38.p7
Start
117796156 (Hg38)
End
117796156 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02147
Nearest miRNA
hsa-mir-10397/Upstream/1540322; hsa-mir-103a-1/Downstream/1178430;
Nearest TSS
ENST00000502646/Upstream/340893; ENST00000509669/Downstream/128852;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1219468, chr5-CpG: 69/Downstream/1191996
Nearby gene
LINC00992(-249858) ;
Downstream sequence
GAACAGTGACCCCATACATGTTAAGCCTAA
Junction sequence
TCTGCGCACCAGCACCATGCAACTTTTTCAGAACAGTGACCCCATACATGTTAAGCCTAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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