hsa-mir-1304-5p _LIHC.png
KLHL32 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000153
Fusion event
HBV-KLHL32 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1796
Integrated sequence
CTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAAT| |TGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTT
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh38.p7
Start
97132699 (Hg38)
End
97132699 (Hg38)
Orient
-
Location type
Intronic
Target gene
KLHL32
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-6765-5p ; hsa-mir-1304-5p ; hsa-mir-1827 ; hsa-mir-4693-3p ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-3200-5p ; hsa-mir-641 ; hsa-mir-3617-5p
Nearest miRNA
hsa-mir-10398/Upstream/5610962; hsa-mir-1202/Downstream/891832;
Nearest TSS
ENST00000381078/Upstream/68071; ENST00000574739/Downstream/29346;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/207712, chr6-CpG: 53/Downstream/150121
Downstream sequence
TCTTTGTACTAGGAGGCTGTAGGCATAAAT
Junction sequence
TAAATATATTCTCCCATTATGGACAGCAACTCTTTGTACTAGGAGGCTGTAGGCATAAAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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