Basic Information
VIS ID
TVIS10000161
Fusion event
HBV-chr7 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1813
Integrated sequence
AGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCA| |CCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGA
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh38.p7
Start
38691316 (Hg38)
End
38691316 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1183/Upstream/1771884; hsa-mir-10399/Downstream/4459579;
Nearest TSS
ENST00000635602/Upstream/59749; ENST00000464276/Downstream/35870;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/59755, chr7-CpG: 36/Downstream/284627
Nearby gene
FAM183BP(-4279) ;
Downstream sequence
TGTAGGCATAAATTGGTCTGCGCACCAGCA
Junction sequence
ACTCTGTAAAATATTTGAAAAGATTTATTCTGTAGGCATAAATTGGTCTGCGCACCAGCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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