Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000191
Fusion event
HBV-CELF2 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
End
1808
Integrated sequence
TTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCAC| |CAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGAC
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
Start
End
11151997 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-375 ; hsa-mir-324-5p ; hsa-let-7e-5p ; hsa-mir-95-3p ; hsa-mir-4717-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-192-3p ; hsa-mir-124-5p ; hsa-mir-4275 ; hsa-mir-203a-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-642a-5p ; hsa-mir-329-5p ; hsa-mir-4748 ; hsa-mir-4464
Nearest miRNA
hsa-mir-3155a/Upstream/4999720; hsa-mir-107/Downstream/978763;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/133203, chr10-CpG: 32/Downstream/13623
Downstream sequence
GAGGCTGTAGGCATAAATTGGTCTGCGCAC
Junction sequence
TGAACAGCACTTCTTTTTCTCTTTACCAAGGAGGCTGTAGGCATAAATTGGTCTGCGCAC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).