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VISDB
Viral Integration Site DataBase
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TVIS10000192
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000192
Fusion event
HBV-BEND7 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1802
Integrated sequence
GCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCT| |GCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGC
Host Sequence
Chromosome
chr10
Cytoband
p13
Reference genome
GRCh38.p7
Start
13441600 (Hg38)
End
13441600 (Hg38)
Orient
+
Location type
Intronic
Target gene
BEND7
Nearest miRNA
hsa-mir-3155a/Upstream/716247; hsa-mir-107/Downstream/941600;
Nearest TSS
ENST00000439456/Upstream/26398;
ENST00000438431/Downstream/11014;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/92660
,
chr10-CpG: 21/Downstream/30307
Downstream sequence
ATACTCATCCTATTTTAACACGGCGAAAGG
Junction sequence
TACTAAAAAACTGTAAACATAAATTGGTCTATACTCATCCTATTTTAACACGGCGAAAGG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Sample Information
×
Sample name
Huh7-NTCP
Sample type
Cell line
Gender
Female
CpG Island Information
×
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