TCERG1L _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000199
Fusion event
HBV-TCERG1L integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1811
Integrated sequence
AAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh38.p7
Start
131236464 (Hg38)
End
131236464 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
TCERG1L
Nearest miRNA
hsa-mir-107/Upstream/273796; hsa-mir-202/Downstream/2011047;
Nearest TSS
ENST00000439456/Upstream/141246; ENST00000634373/Downstream/23872;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/141039, chr10-CpG: 25/Downstream/23611
Downstream sequence
GCTGTAGGCATAGATTGGTCTGCGCACCAG
Junction sequence
GCATCCCAGGGTCACCGTGCCCTGTGGCTAGCTGTAGGCATAGATTGGTCTGCGCACCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate