hsa-mir-130b-3p _LIHC.png
PDE3B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000202
Fusion event
HBV-PDE3B integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1827
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh38.p7
Start
14747156 (Hg38)
End
14747156 (Hg38)
Orient
-
Location type
Intronic
Target gene
PDE3B
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-128-3p ; hsa-mir-124-3p ; hsa-mir-93-5p ; hsa-mir-16-5p ; hsa-mir-562 ; hsa-mir-3119 ; hsa-mir-4735-5p ; hsa-mir-5683
Nearest miRNA
hsa-mir-210/Upstream/2583389; hsa-let-7a-2/Downstream/1222377;
Nearest TSS
ENST00000527297/Upstream/48317; ENST00000525439/Downstream/41783;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/102028, chr11-CpG: 68/Downstream/144198
Downstream sequence
GGTCTGCGCACCAGCACCATGCAACTTTTT
Junction sequence
TTGTTTAAAAGATTATGTTGTTTTAAAGATGGTCTGCGCACCAGCACCATGCAACTTTTT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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