Basic Information
VIS ID
TVIS10000217
Fusion event
HBV-C13orf42 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1811
Integrated sequence
AAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh38.p7
Start
51089161 (Hg38)
End
51089161 (Hg38)
Orient
+
Location type
Intronic
Target gene
C13orf42
Nearest miRNA
hsa-mir-15a/Upstream/1039960; hsa-mir-1267/Downstream/259406;
Nearest TSS
ENST00000623511/Upstream/141097; ENST00000614264/Downstream/22048;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/178706, chr13-CpG: 86/Downstream/132820
Downstream sequence
GCTGTAGGCATAAATTGGTCTGCGCACCAG
Junction sequence
GGTGTGTCAGGAAAGAAAACAGCATCTCTAGCTGTAGGCATAAATTGGTCTGCGCACCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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