Basic Information
VIS ID
TVIS10000223
Fusion event
HBV-LINC02325 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1787
Integrated sequence
ACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTA| |GGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTT
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
GRCh38.p7
Start
97576984 (Hg38)
End
97576984 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02325
Nearest miRNA
hsa-mir-1260a/Upstream/2438998; hsa-mir-1185-1/Downstream/2532435;
Nearest TSS
ENST00000550708/Upstream/118114; ENST00000557072/Downstream/109643;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/357375, chr14-CpG: 53/Downstream/1541084
Downstream sequence
GATTAAAGGTCTTTGTACTAGGAGGCTGTA
Junction sequence
TATTTCTAAATTGCATATTTCAAAATAAAAGATTAAAGGTCTTTGTACTAGGAGGCTGTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate