VISDB Viral Integration Site DataBase

VIS ID

TVIS10000227

Fusion event

HBV-PKM integration

Validated

Yes

Detection method

invPCR

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

End

1827

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT

Chromosome

chr15

Cytoband

q23

Reference genome

Start

End

72200961 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-326 ; hsa-mir-122-5p ; hsa-mir-30a-5p ; hsa-mir-1301-3p ; hsa-mir-935 ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-296-3p ; hsa-mir-766-3p ; hsa-mir-769-5p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-324-3p ; hsa-mir-328-3p ; hsa-mir-330-3p ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-30c-5p ; hsa-mir-92a-3p ; hsa-mir-23a-3p ; hsa-mir-1260b ; hsa-mir-3187-3p ; hsa-mir-218-5p ; hsa-mir-6730-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-6515-5p ; hsa-mir-4727-3p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-4668-5p ; hsa-mir-6822-3p ; hsa-mir-504-3p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-3659 ; hsa-mir-6804-5p ; hsa-mir-17-3p ; hsa-mir-4254 ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-4650-5p ; hsa-mir-1296-3p ; hsa-mir-4694-3p ; hsa-mir-338-3p ; hsa-let-7a-5p ; hsa-mir-369-3p ; hsa-mir-184 ; hsa-mir-1205 ; hsa-mir-1238-5p ; hsa-mir-1285-3p ; hsa-mir-1286 ; hsa-mir-1302 ; hsa-mir-153-5p ; hsa-mir-1587 ; hsa-mir-185-3p ; hsa-mir-185-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-3135b ; hsa-mir-3144-5p ; hsa-mir-3176 ; hsa-mir-3179 ; hsa-mir-3187-5p ; hsa-mir-3191-3p ; hsa-mir-330-5p ; hsa-mir-3620-5p ; hsa-mir-3652 ; hsa-mir-378g ; hsa-mir-3909 ; hsa-mir-3922-3p ; hsa-mir-3945 ; hsa-mir-4253 ; hsa-mir-4263 ; hsa-mir-4271 ; hsa-mir-4298 ; hsa-mir-4306 ; hsa-mir-432-3p ; hsa-mir-4430 ; hsa-mir-4436a ; hsa-mir-4481 ; hsa-mir-4486 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-4534 ; hsa-mir-4644 ; hsa-mir-4648 ; hsa-mir-4651 ; hsa-mir-4652-5p ; hsa-mir-4656 ; hsa-mir-4675 ; hsa-mir-4722-5p ; hsa-mir-4725-3p ; hsa-mir-4731-5p ; hsa-mir-4741 ; hsa-mir-4745-5p ; hsa-mir-4747-5p ; hsa-mir-4758-5p ; hsa-mir-491-5p ; hsa-mir-5000-3p ; hsa-mir-5001-5p ; hsa-mir-5189-5p ; hsa-mir-5192 ; hsa-mir-5196-5p ; hsa-mir-552-3p ; hsa-mir-576-5p ; hsa-mir-5787 ; hsa-mir-6085 ; hsa-mir-608 ; hsa-mir-612 ; hsa-mir-637 ; hsa-mir-6732-5p ; hsa-mir-6752-5p ; hsa-mir-6756-5p ; hsa-mir-6758-5p ; hsa-mir-6766-5p ; hsa-mir-6780a-3p ; hsa-mir-6780b-5p ; hsa-mir-6810-5p ; hsa-mir-6813-5p ; hsa-mir-6829-5p ; hsa-mir-6842-5p ; hsa-mir-6852-3p ; hsa-mir-6856-5p ; hsa-mir-6860 ; hsa-mir-6862-5p ; hsa-mir-6894-5p ; hsa-mir-7110-5p ; hsa-mir-7154-3p ; hsa-mir-762 ; hsa-mir-764 ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-8077 ; hsa-mir-873-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-10393/Upstream/2121493; hsa-mir-11181/Downstream/386256;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/3186, chr15-CpG: 179/Downstream/28829

Downstream sequence

GGTCTGCGCACCAGCACCATGCAACTTTTT

Junction sequence