Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene2935338229258969292702852927570029280521292878022929250129271006292734902926227329264479292942932929635229296416292979502929964029301172292846162928596929257320292582942927360029274200292722202927277229256054292563732929313029293303292708432927086829304718
Basic Information
VIS ID
TVIS10000231
Fusion event
HBV-SNX29P2 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1792
Integrated sequence
CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh38.p7
Start
29304718 (Hg38)
End
29304718 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNX29P2
Nearest miRNA
hsa-mir-1225/Upstream/346057; hsa-mir-11401/Downstream/294461;
Nearest TSS
ENST00000527434/Upstream/32498; ENST00000567248/Downstream/92978;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/5628, chr16-CpG: 146/Downstream/149314
Downstream sequence
AAGGTCTTTGTACTAGGAGGCTGTAGGCAT
Junction sequence
CATGGAATGCCATTCATGCACATGGAAAGAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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