CYTH1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000240
Fusion event
HBV-CYTH1 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1828
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh38.p7
Start
78763834 (Hg38)
End
78763834 (Hg38)
Orient
-
Location type
Intronic
Target gene
CYTH1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-34a-5p ; hsa-mir-1827 ; hsa-mir-3940-3p
Nearest miRNA
hsa-mir-10226/Upstream/1366780; hsa-mir-1250/Downstream/943342;
Nearest TSS
ENST00000595228/Upstream/26867; ENST00000587434/Downstream/18438;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/260841, chr17-CpG: 155/Downstream/17594
Downstream sequence
GTCTGCGCACCAGCACCATGCAACTGTTTC
Junction sequence
CTGGGCCATTCTACGTTTGAAAGATGATGGGTCTGCGCACCAGCACCATGCAACTGTTTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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