Basic Information
VIS ID
TVIS10000241
Fusion event
HBV-ENDOV integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1816
Integrated sequence
CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh38.p7
Start
80434236 (Hg38)
End
80434236 (Hg38)
Orient
-
Location type
Intronic
Target gene
ENDOV
Nearest miRNA
hsa-mir-10226/Upstream/14743; hsa-mir-1250/Downstream/691040;
Nearest TSS
ENST00000595228/Upstream/8732; ENST00000573746/Downstream/20493;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/18314, chr17-CpG: 22/Downstream/9799
Downstream sequence
AGGCATAAATTGGTCTGCGCACCAGCACCA
Junction sequence
CCAAGAAAATGAAGCCAGACAGAAAAGACTAGGCATAAATTGGTCTGCGCACCAGCACCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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