PLIN4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000245
Fusion event
HBV-PLIN4 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1778
Integrated sequence
GCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAG| |GAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAG
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh38.p7
Start
4519810 (Hg38)
End
4519810 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PLIN4
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1227/Upstream/73762; hsa-let-7e/Downstream/250860;
Nearest TSS
ENST00000633603/Upstream/1345; ENST00000598107/Downstream/6039;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/25316, chr19-CpG: 36/Downstream/3870
Nearby gene
PLIN4(-2106) ; PLIN5(+2721) ;
Downstream sequence
AGGAGATTAGATTAAAGGTCTTTGTACTAG
Junction sequence
AGCCCAGTGTGTGGAGAGAAAAAATTAAAAAGGAGATTAGATTAAAGGTCTTTGTACTAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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