ZSCAN18 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000251
Fusion event
HBV-ZSCAN18 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh38.p7
Start
58119246 (Hg38)
End
58119246 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZSCAN18
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-92b-3p
Nearest miRNA
hsa-let-7e/Upstream/2731004; hsa-mir-10394/Downstream/215442;
Nearest TSS
ENST00000633603/Upstream/819; ENST00000594248/Downstream/23418;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/372, chr19-CpG: 62/Downstream/31124
Downstream sequence
TAGGCATAAATTGGTCTGCGCACCAGCACC
Junction sequence
CGATCACATAAAATGATTATTGTGCCCTGGTAGGCATAAATTGGTCTGCGCACCAGCACC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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