Basic Information
VIS ID
TVIS10000252
Fusion event
HBV-CENPBD1P1 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1810
Integrated sequence
CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh38.p7
Start
58583120 (Hg38)
End
58583120 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
CENPBD1P1
Nearest miRNA
hsa-let-7e/Upstream/32744;
Nearest TSS
ENST00000633603/Upstream/9545; ENST00000596029/Downstream/16157;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/1214, None/Downstream
Nearby gene
MZF1-AS1(-8323) ;
Downstream sequence
GGCTGTAGGCATAAATTGGTCTGCGCACCA
Junction sequence
ATCCAGGGCCCGGGAAGAACAGAGCTGGAAGGCTGTAGGCATAAATTGGTCTGCGCACCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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