Basic Information
VIS ID
TVIS10000255
Fusion event
HBV-LOC100505664 integration
Validated
Yes
Detection method
invPCR
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
29437961
Virus Sequence
Virus name
HBV
Reference genome
U95551.1
End
1828
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh38.p7
Start
23168747 (Hg38)
End
23168747 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC100505664
Nearest miRNA
hsa-mir-103a-2/Upstream/4698056; hsa-mir-1-1/Downstream/3039439;
Nearest TSS
ENST00000382410/Upstream/36126; ENST00000622708/Downstream/11429;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/117166, chr20-CpG: 129/Downstream/181252
Nearby gene
RNA5SP478(-7776) ; RHO(+11429) ;
Downstream sequence
GTCTGCGCACCAGCACCATGCAACTTTTTC
Junction sequence
TTCTTTTTCTTGCTTAACATCATTTCTGTTGTCTGCGCACCAGCACCATGCAACTTTTTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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