Basic Information
VIS ID
TVIS10000349
Fusion event
HBV-LOC107985242 integration
Validated
Yes
Detection method
invPCR+NAH
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28414318
Virus Sequence
Virus name
HBV
Subtype
A
Reference genome
X70185.1
Start
1603
End
1664
Integrated sequence
TTGCATGGAGACCACCGTGAACGCCCATCAGATCCTGCCCAAGGTCTTACATAAGAGGACTC
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
194161891/194192761 (Hg38)
End
194161910/194192780 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
LOC107985242
Nearest miRNA
hsa-mir-101-1/Upstream/1056178; hsa-mir-1182/Downstream/2389633;
Nearest TSS
ENST00000473358/Upstream/43288; ENST00000435554/Downstream/158163;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1070667, chr1-CpG: 24/Downstream/2415798
Target sequence
TTAGAGTCTACAGTGTCAT
Reference
Chauhan, R., et al. Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis ,2017,6(4): e317.
Curate