Basic Information
VIS ID
TVIS10000362
Fusion event
HBV-FAM90A11P integration
Validated
Yes
Detection method
invPCR+NAH
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28414318
Virus Sequence
Virus name
HBV
Subtype
A
Reference genome
X70185.1
Start
1603
End
1623
Integrated sequence
TTGCATGGAGACCACCGTGAA
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
7874512/8016990 (Hg38)
End
7874653/8017131 (Hg38)
Location type
Intronic
Target gene
FAM90A11P
Nearest miRNA
hsa-mir-3674/Upstream/1271746; hsa-mir-10400/Downstream/71810;
Nearest TSS
ENST00000518652/Upstream/39005; ENST00000524073/Downstream/172064;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/61574, chr8-CpG: 32/Downstream/10807
Target sequence
GGACCCAGGGAATTAGAGCCTCACAGGCGTCCGGGAGACTTTTCAGGCATAATGCCTGGAGTCGCAAGACGAGCTGAAAAAGGAGCCAGGCACTGAAGGACAAAGCGTTGTTGACTTTCCTCATCTGTGTTTCCCAGTGCG
Reference
Chauhan, R., et al. Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis ,2017,6(4): e317.
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