VISDB Viral Integration Site DataBase

VIS ID

TVIS10000369

Fusion event

HBV-TET1 integration

Validated

Yes

Detection method

invPCR+NAH

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Subtype

A

Reference genome

Start

1668

End

1808

Integrated sequence

GACTCTCAGCAATGTCAACGACCGACCTTGAGGCCTACTTCAAAGACTGTGTGTTTAAGGACTGGGAGGAGCTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTATTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG

Chromosome

chr10

Cytoband

q21.3

Reference genome

Start

End

70434362/68674605 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-21-5p ; hsa-mir-877-5p ; hsa-mir-454-3p ; hsa-mir-141-3p ; hsa-mir-576-5p ; hsa-mir-3686 ; hsa-mir-4263 ; hsa-mir-4735-5p ; hsa-mir-4778-5p ; hsa-mir-5571-5p ; hsa-mir-1305 ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-3065-5p ; hsa-mir-205-3p ; hsa-mir-30a-5p

Nearest miRNA

hsa-mir-1265/Upstream/1270919; hsa-mir-107/Downstream/3116142;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/113264, chr10-CpG: 89/Downstream/46342

Target sequence

CACAGTAGTGGTTGGCAAGAATAAGGCAGCACAAAGGGAGCCAAGAAGAAAGTGCTTGATCCATTTTCTAAGAAAGATTTGTATTACGTGAAAGCATCTGCCATGTTCAATATAAAAAATATTGGGAAGACACTAGTCACCASAACCCAAGGAACCATAATTGAATCTGATGGCCTCAAGGGTCGTGTATTTGAAGTGAGTCTTGCTGATATGCAGAATGATAAAGTTGCATTTAGAAAATTCAGCTGATTACTGAAGATGTTCAGGGGAATGATT