FLRT2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000381
Fusion event
HBV-FLRT2 integration
Validated
Yes
Detection method
invPCR+NAH
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28414318
Virus Sequence
Virus name
HBV
Subtype
A
Reference genome
X70185.1
Start
1603
End
1624
Integrated sequence
TTGCATGGAGACCACCGTGAAC
Host Sequence
Chromosome
chr14
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
86038392/85572048 (Hg38)
End
86038596/85572252 (Hg38)
Location type
Intronic
Target gene
FLRT2
Nearest miRNA
hsa-mir-1260a/Upstream/8305758; hsa-mir-1185-1/Downstream/8375974;
Nearest TSS
ENST00000550708/Upstream/11185; ENST00000553650/Downstream/51438;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/37914, chr14-CpG: 87/Downstream/2420300
Target sequence
CCTCACTGTTGTGTCTGGCATTCACTGCTACAAACAACACAAATCATGTACTTTATATCTTGAAGTTGTCACTCAGCCCCGTGTTTTCTCATTTCTGTGTCTTTACTTAGATCATAAACCTAGGATTTCCTTTTCTCTGCTTATCTAAGTCCTACTCCTCTTTCAAGGCCAATCTTAAGTGGCTTATCTCCAKAAGATACCAGA
Reference
Chauhan, R., et al. Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis ,2017,6(4): e317.
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