Basic Information
VIS ID
TVIS10000384
Fusion event
HBV-FAM90A23P integration
Validated
Yes
Detection method
invPCR+NAH
Data source
Curated
Sample type
Cell line
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28414318
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
AB033556.1
Start
1625
End
1606
Integrated sequence
CATGGAAACCACCGTGAACA
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
7441825/7584303 (Hg38)
End
7442040/7584518 (Hg38)
Location type
Intronic
Target gene
FAM90A23P
Nearest miRNA
hsa-mir-3674/Upstream/839059; hsa-mir-10400/Downstream/504423;
Nearest TSS
ENST00000518652/Upstream/44675; ENST00000335186/Downstream/196895;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/55380, chr8-CpG: 56/Downstream/26734
Target sequence
TTGGACCGCACTGGGAAACACAGATGAGGAAAGTCAACAACGCTTTGTCCTTCAGTGCCTGGCTCCTTTTTCAGCTCGTCTTGCGACTCCAGGCATTATGCCTGAAAAGTCTCCCGGACGCCTGTGAGGCTCTAATTCCCTGGGTCCCATTGCCATGTCTCTGGATTTGCGAAGATCCACCGCACCCTCTGTGGAACTCCCGTGTCGGTGAACTT
Reference
Chauhan, R., et al. Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis ,2017,6(4): e317.
Curate