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VISDB
Viral Integration Site DataBase
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TVIS10000406
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000406
Fusion event
HBV-FN1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2015
PubMed ID
25901726
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
End
458
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
216253024/215388301 (Hg38)
End
216253024/215388301 (Hg38)
Orient
+
Location type
Intronic
Target gene
FN1
miRNAs that regulate target gene
hsa-mir-200c-3p
;
hsa-mir-200b-3p
;
hsa-mir-1-3p
;
hsa-let-7g-5p
;
hsa-mir-26b-5p
;
hsa-mir-615-3p
;
hsa-mir-218-5p
;
hsa-mir-140-3p
Nearest miRNA
hsa-mir-10b/Upstream/1630142; hsa-mir-1244-1/Downstream/2512212;
Nearest TSS
ENST00000437798/Upstream/4221;
ENST00000412951/Downstream/4846;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/75892
,
chr2-CpG: 43/Downstream/47243
Upstream sequence
TCACTACATATTCTGTACCAGGCAGGAGAT
Junction sequence
TCACTACATATTCTGTACCAGGCAGGAGATcttggtagtccagaagaaccaacaagaaga
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Dong, H., et al. Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma. PLoS One,2015, 10(4): e0123175.
Sample Information
×
Sample name
355N
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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