hsa-mir-892b _LIHC.png
CCNE1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000408
Fusion event
HBV-CCNE1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2015
PubMed ID
25901726
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
End
343
Host Sequence
Chromosome
chr19
Cytoband
q12
Reference genome
GRCh37/hg19
Start
30313234/29822327 (Hg38)
End
30313234/29822327 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCNE1
miRNAs that regulate target gene
hsa-mir-15b-5p ; hsa-mir-503-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-185-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-16-1-3p ; hsa-mir-195-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-151a-3p ; hsa-mir-342-5p ; hsa-mir-125b-5p ; hsa-mir-92a-3p ; hsa-mir-383-3p ; hsa-mir-497-5p ; hsa-mir-4524a-5p ; hsa-mir-4694-3p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-7-5p ; hsa-mir-4477a ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-5191 ; hsa-mir-646 ; hsa-mir-25-5p ; hsa-mir-30c-2-3p ; hsa-mir-144-5p ; hsa-mir-892b
Nearest miRNA
hsa-mir-10395/Upstream/9422973; hsa-let-7e/Downstream/5300373;
Nearest TSS
ENST00000633603/Upstream/595; ENST00000585655/Downstream/101317;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/9553, chr19-CpG: 21/Downstream/21206
Nearest cancer related gene
CCNE1(OG, No orient, 0)
Upstream sequence
CTGCTTCGGCCTTGTATCATTTCTCGTCAT
Junction sequence
CTGCTTCGGCCTTGTATCATTTCTCGTCATctcttgtcctccaatttgtcctggctatcg
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Dong, H., et al. Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma. PLoS One,2015, 10(4): e0123175.
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