hsa-mir-6826-3p _LIHC.png
hsa-mir-1304-5p _LIHC.png
TPT1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000415
Fusion event
HBV-TPT1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2015
PubMed ID
25901726
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
End
323
Host Sequence
Chromosome
chr13
Cytoband
q14.13
Reference genome
GRCh37/hg19
Start
45914856/45914856 (Hg38)
End
45914856/45914856 (Hg38)
Orient
+
Location type
Intronic
Target gene
TPT1
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-374b-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-29b-3p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-3200-3p ; hsa-mir-544a ; hsa-mir-1304-5p ; hsa-mir-6765-5p ; hsa-mir-3926 ; hsa-mir-6089 ; hsa-mir-5008-5p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-100-3p ; hsa-mir-6826-3p ; hsa-mir-6069 ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p
Nearest miRNA
hsa-mir-2276/Upstream/1718656; hsa-mir-1267/Downstream/4081559;
Nearest TSS
ENST00000623511/Upstream/63120; ENST00000606351/Downstream/96699;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/200777, chr13-CpG: 51/Downstream/137463
Upstream sequence
CCTTCTGTCCTACTGACCATCTTCCCCTCC
Junction sequence
CCTTCTGTCCTACTGACCATCTTCCCCTCCacctccaatcactcaccaacctcttgtccc
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Dong, H., et al. Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma. PLoS One,2015, 10(4): e0123175.
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