Basic Information
VIS ID
TVIS10000432
Fusion event
HBV-COX10-AS1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2015
PubMed ID
25901726
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
End
457
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
13933678/14030361 (Hg38)
End
13933678/14030361 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA17A
Target gene
COX10-AS1
Nearest miRNA
hsa-mir-1253/Upstream/486715; hsa-mir-10226/Downstream/1221266;
Nearest TSS
ENST00000595228/Upstream/63409; ENST00000429152/Downstream/39135;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/428119, chr17-CpG: 41/Downstream/38952
Downstream sequence
Gccatccatgtaagacatgacttgctg
Junction sequence
TCTTCTTGTTGGTTCTTCTGGACTACCAAGccatccatgtaagacatgacttgctg
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Dong, H., et al. Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma. PLoS One,2015, 10(4): e0123175.
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