Basic Information
VIS ID
TVIS10000445
Fusion event
HBV-LOC110806263 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1298519/1298404 (Hg38)
End
1298519/1298404 (Hg38)
Location type
Intronic
Target gene
LOC110806263
Nearest miRNA
hsa-mir-4635/Upstream/235430; hsa-mir-10397/Downstream/10906;
Nearest TSS
ENST00000502646/Upstream/3335; ENST00000605200/Downstream/23425;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2549, chr5-CpG: 18/Downstream/36558
Nearby gene
TERT(-3357) ; MIR4457(+10906) ;
Downstream sequence
AATCCTTCGGGCCTCCCTGCAGGCCCGAAAAGTAATCCAAAGGTTCTGGGAAGAGGCGGGCAGGAGGGTCAGAGGGGGGCAGCCTCAGGACGATGGAGGCAGTCAGTCTGAGGCTGAAAAGGGAGGGAGGGCCTCGAGCCCAGGCCTGCAAGCGCCTCCAGAAGCTGGAAAAAGCGGGGAAGGGACCCTCCACGGAGCCTGCAG
Junction sequence
TCCACAGAGTATGTAAATAATGCCTAGTTTTGAAGTAATGATTAACTGCATGTTCAGGATAATATGGTTTAATGCCTTTGTCCAAGGGCAAATCCTTCGGGCCTCCCTGCAGGCCCGAAAAGTAATCCAAAGGTTCTGGGAAGAGGCGGGCAGGAGGGTCAGAGGGGGGCAGCCTCAGGACGATGGAGGCAGTCAGTCTGAGGCTGAAAAGGGAGGGAGGGCCTCGAGCCCAGGCCTGCAAGCGCCTCCAGAAGCTGGAAAAAGCGGGGAAGGGACCCTCCACGGAGCCTGCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate