Basic Information
VIS ID
TVIS10000450
Fusion event
HBV-chr13 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
106574177/105921828 (Hg38)
End
106574177/105921828 (Hg38)
Nearest miRNA
hsa-mir-1297/Upstream/3875824; hsa-mir-1267/Downstream/1609343;
Nearest TSS
ENST00000623511/Upstream/231399; ENST00000643760/Downstream/452649;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/3075415, chr13-CpG: 29/Downstream/571232
Nearby gene
LINC00343(-160034) ; LINC00460(+454734) ;
Downstream sequence
CGATCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAACCACAATGCCCG
Target sequence
AATCCAAAATTGATGTTTGCACTTCAGTAGTAAATCATTGAAGATGGAGAAATTATGCCAAGTGACTCTCTCAAGCCTTTTTAACTCAGACGCACTGCCTCCTCAATCAGCTCAGCAGATAAACCTCAACTACCTTAAGCAAAGACTTCCTTACTTTTACACTTTCAGTCTCTGTCTCCCCACTTTTCCTTCCAACTTCTGACTTTTGATGACTCTTACTTCCATACCTTCCCTCTCTTTTCCACTGCCCTCCTT
Junction sequence
CCAGATTGGGACTTCAACCCCAACAAGGATCACTGGCCAGAGGCAAATCAGGTAGGAGCGGGAGCATTCGGGCCAGGGTTCACTCGATCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAACCACAATGCCCG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate