ME1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000451
Fusion event
HBV-ME1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
83965335/83255616 (Hg38)
End
83965335/83255616 (Hg38)
Location type
Intronic
Target gene
ME1
miRNAs that regulate target gene
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-10398/Upstream/4716307; hsa-mir-1202/Downstream/7057126;
Nearest TSS
ENST00000381078/Upstream/61680; ENST00000369700/Downstream/175455;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/61558, chr6-CpG: 60/Downstream/175077
Downstream sequence
TTTATGGTATAGCTTGTTTTTTTAATCTATGGCCTAACAGTAAAAGTATACCAGAT
Junction sequence
CTGCCTCTTCGTCTAACAACAGTAGTTTCCGGAAGTGTTGATAAGATAGGGGCATTTGGTGGTCTATATGCAGGAGGAGTGCGAATCCACACTCCAAAAGACACCAAATATTCAAGAACAGTTTCTCTCCCAAAAGTAAGACAGGAAATGTGAAACCACAATAGTTGTCTGATTTTTAGGCCCATATTTATGGTATAGCTTGTTTTTTTAATCTATGGCCTAACAGTAAAAGTATACCAGAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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