Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000456
Fusion event
HBV-TCERG1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
End
145855469/146475906 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-877-3p ; hsa-mir-769-5p ; hsa-mir-615-3p ; hsa-mir-328-3p ; hsa-mir-222-3p ; hsa-let-7a-5p ; hsa-mir-299-5p ; hsa-mir-296-3p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-3163 ; hsa-mir-5701 ; hsa-mir-29b-2-5p ; hsa-mir-4703-3p ; hsa-mir-5011-5p ; hsa-mir-5000-5p ; hsa-mir-410-3p ; hsa-mir-6868-3p ; hsa-mir-1283 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418
Nearest miRNA
hsa-mir-10397/Upstream/2795935; hsa-mir-103a-1/Downstream/2586407;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/28039, chr5-CpG: 97/Downstream/401877
Downstream sequence
AACCTATGAATAATACTCAAACCAACTCACTATTCTGAAAACTGCTAAGCCCTTCCCTTCCTATACAA
Junction sequence
ATGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCCCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTCGGGGGAGGAGATTAGGTTAATGATCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCAAACCTATGAATAATACTCAAACCAACTCACTATTCTGAAAACTGCTAAGCCCTTCCCTTCCTATACAA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.