VISDB Viral Integration Site DataBase

VIS ID

TVIS10000469

Fusion event

HBV-UBE2H integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr7

Cytoband

q32.2

Reference genome

Start

End

129551161/129911321 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-451a ; hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-1915-5p ; hsa-mir-501-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-mir-4643 ; hsa-mir-218-5p ; hsa-mir-6885-3p ; hsa-mir-302c-5p ; hsa-mir-3977 ; hsa-mir-6844 ; hsa-mir-3143 ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-4803 ; hsa-mir-10a-3p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-4668-5p ; hsa-mir-922 ; hsa-mir-5584-5p ; hsa-mir-335-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-342-3p ; hsa-mir-4639-3p ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-7156-3p ; hsa-mir-6873-3p ; hsa-mir-3941 ; hsa-mir-8064 ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-6728-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4691-3p ; hsa-mir-449b-3p ; hsa-mir-4789-3p ; hsa-mir-377-3p ; hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-627-3p ; hsa-mir-5697 ; hsa-mir-338-5p ; hsa-mir-362-3p ; hsa-mir-329-3p

Nearest miRNA

hsa-mir-10525/Upstream/136307; hsa-mir-10399/Downstream/584790;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/85017, chr7-CpG: 88/Downstream/40871

Downstream sequence

CACACCATTGCACCACTCCAGCCTGGGTGACAGAGTGAGACTCCGTCTCAATTAAAAAAAAAAATGAGGACAGAACAAACAGGATGAGGGAGGTTGTT

Junction sequence